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Bithionol

VETRANAL®, analytical standard

Sinonimo/i:

2,2′-Thio-bis(4,6-dichlorophenol), Bis(2-hydroxy-3,5-dichlorophenyl) sulfide

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CHF 53.30

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About This Item

Formula empirica (notazione di Hill):
C12H6Cl4O2S
Numero CAS:
97-18-7
Peso molecolare:
356.05
Beilstein:
2003535
Numero CE:
202-565-0
Numero MDL:
MFCD00055727
Codice UNSPSC:
41116107
ID PubChem:
329753850
NACRES:
NA.24

CHF 53.30

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Grado

analytical standard

Livello qualitativo

100

Nome Commerciale

VETRANAL®

Durata

limited shelf life, expiry date on the label

tecniche

HPLC: suitable
gas chromatography (GC): suitable

Spettro attività antibiotica

parasites

applicazioni

cleaning products
clinical
cosmetics
food and beverages
forensics and toxicology
personal care
pharmaceutical (small molecule)

Formato

neat

Modalità d’azione

enzyme | inhibits
protein synthesis | interferes

Stringa SMILE

Oc1c(Cl)cc(Cl)cc1Sc2cc(Cl)cc(Cl)c2O

InChI

1S/C12H6Cl4O2S/c13-5-1-7(15)11(17)9(3-5)19-10-4-6(14)2-8(16)12(10)18/h1-4,17-18H
JFIOVJDNOJYLKP-UHFFFAOYSA-N

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Categorie correlate

Descrizione generale

Bithionol is a dichlorophenol compound that shows antimicrobial property.1
Chemical structure: diphenylsulfide

Applicazioni

Bithionol has been used as reference standard for measuring the concentration of antihelmintic substance in pharmacy products using HPLC.2
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Prodotti consigliati

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Note legali

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Pittogrammi

Skull and crossbones
GHS06

Avvertenze

Danger

Indicazioni di pericolo

H300

Classi di pericolo

Acute Tox. 2 Oral

Codice della classe di stoccaggio

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

Classe di pericolosità dell'acqua (WGK)

WGK 3

Dispositivi di protezione individuale

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

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Certificati d'analisi (COA)

Lot/Batch Number
BCCG4854
BCBW2025

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Renee L Florent et al.
Veterinary parasitology, 144(3-4), 197-207 (2006-11-30)
This study examined the toxicity of bithionol to Atlantic salmon Salmo salar and rainbow trout Oncorhynchus mykiss in fresh- and seawater and the efficacy of bithionol as a 1h seawater bath treatment for amoebic gill disease (AGD). To examine toxicity
R L Florent et al.
Journal of fish diseases, 32(5), 391-400 (2009-02-27)
This study examined the efficacy of bithionol as a prophylactic or therapeutic oral treatment for Atlantic salmon (AS), Salmo salar, affected by amoebic gill disease (AGD). Furthermore, it explored the interaction of bithionol oral therapy with the current standard treatment
Renee L Florent et al.
Diseases of aquatic organisms, 91(3), 257-262 (2010-12-08)
The objective of the present study was to evaluate the in vitro toxicity of bithionol and bithionol sulphoxide to Neoparamoeba spp., the causative agent of amoebic gill disease (AGD). The current treatment for AGD-affected Atlantic salmon involves bathing sea-caged fish
L Reid et al.
Toxicology in vitro : an international journal published in association with BIBRA, 15(4-5), 441-445 (2001-09-22)
Exposure to hydrogen peroxide causes oxidative stress in keratinocytes. Previous work has shown that the antiparasitic drug bithionol has an EC(50) of 0.7 microg/ml (2 microM) with primary human keratinocytes, but that these cells do not respond to photoactivated bithionol.
E Durbize et al.
Contact dermatitis, 48(3), 144-149 (2003-05-21)
Contact photoallergy to ketoprofen gels has been widely reported, and cross-sensitivity reactions with other compounds, such as tiaprofenic acid, fenofibrate and benzophenones, are well known. However, positive photopatch tests to other different non-benzophenone-related compounds have recently been observed. We report
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