03394
Poli(etilenglicole)
tested according to Ph. Eur., 6,000
Sinonimo/i:
PEG
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About This Item
Formula condensata:
H(OCH2CH2)nOH
Numero CAS:
Numero MDL:
Codice UNSPSC:
12352104
ID PubChem:
NACRES:
NA.21
Prodotti consigliati
agenzia
tested according to Ph. Eur.
Livello qualitativo
Forma fisica
solid
PM
5000-7000
Solubilità
aliphatic hydrocarbons: slightly soluble
organic solvents: soluble
applicazioni
pharmaceutical (small molecule)
Stringa SMILE
C(CO)O
InChI
1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2
LYCAIKOWRPUZTN-UHFFFAOYSA-N
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Applicazioni
Poly(ethylene glycol) was used as hydrophilic carriers for characterizing the sirolimus solid dispersion nanoparticles.
Azioni biochim/fisiol
Polyethylene glycol (PEG) is a condensation polymer of ethylene oxide and water. It enhances the refolding of extracted proteins. This enables characterization of crystallized proteins.
Nota sulla preparazione
Poly(ethylene glycol) dissolves in many organic solvents and is readily soluble in aromatic hydrocarbons. It also slightly dissolves in aliphatic hydrocarbons.
Codice della classe di stoccaggio
11 - Combustible Solids
Classe di pericolosità dell'acqua (WGK)
WGK 1
Punto d’infiammabilità (°F)
Not applicable
Punto d’infiammabilità (°C)
Not applicable
Dispositivi di protezione individuale
Eyeshields, Gloves, type N95 (US)
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I clienti hanno visto anche
J L Cleland et al.
The Journal of biological chemistry, 267(19), 13327-13334 (1992-07-05)
Polyethylene glycol (PEG) inhibited aggregation during refolding of bovine carbonic anhydrase B (CAB) through the formation of a nonassociating PEG-intermediate complex. Stoichiometric concentrations of PEG were required for complete recovery of active protein during refolding at aggregating conditions. For example
J L Cleland et al.
Bio/technology (Nature Publishing Company), 10(9), 1013-1019 (1992-09-01)
Previous studies on the refolding of recombinant bovine carbonic anhydrase B (CAB) indicated that polyethylene glycol (PEG) significantly enhanced the recovery of active protein by reducing aggregation. To further test the ability of PEG to enhance refolding, three recombinant human
Min-Soo Kim et al.
International journal of nanomedicine, 6, 2997-3009 (2011-12-14)
The aim of this study was to improve the physicochemical properties and bioavailability of poorly water-soluble sirolimus via preparation of a solid dispersion of nanoparticles using a supercritical antisolvent (SAS) process. First, excipients for enhancing the stability and solubility of
I L Konorova et al.
Patologicheskaia fiziologiia i eksperimental'naia terapiia, (4)(4), 7-9 (1991-07-01)
The search for antiaggregatory compounds is undertaken, as a rule, under in vitro conditions which do not reflect the dynamics of the real process. The present work deals with study of the peculiarities of the development of the collagen induced
P I Polimeni et al.
Journal of cardiovascular pharmacology, 14(3), 374-380 (1989-09-01)
The acute hemodynamic effects of an intravenously (i.v.) injected poly(ethylene oxide), Polyox WSR N-60K (dose 50 mg/kg), were studied in the open-chest rat anesthetized with sodium pentobarbital. The injectate is one of four drag-reducing polymers known to augment in vitro
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