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01700

Sigma-Aldrich

Acrylamide

purum, ≥98.0% (GC)

Sinonimo/i:

2-Propenamide, Polyacrylamide, acrylic amide, akrylamid, Acrylic acid amide

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About This Item

Formula condensata:
CH2=CHCONH2
Numero CAS:
79-06-1
Peso molecolare:
71.08
Beilstein:
605349
Numero CE:
201-173-7
Numero MDL:
MFCD00008032
Codice UNSPSC:
41105319
eCl@ss:
39031205
ID PubChem:
329747349
NACRES:
NB.22

Densità del vapore

2.45 (vs air)

Livello qualitativo

200

Tensione di vapore

0.03 mmHg ( 40 °C)

Grado

purum

Saggio

≥98.0% (GC)

P. eboll.

125 °C/25 mmHg (lit.)

Punto di fusione

81-87 °C
82-86 °C (lit.)

Solubilità

water: soluble 200 g/L at 20 °C

Temperatura di conservazione

room temp

Stringa SMILE

NC(=O)C=C

InChI

1S/C3H5NO/c1-2-3(4)5/h2H,1H2,(H2,4,5)
HRPVXLWXLXDGHG-UHFFFAOYSA-N

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Applicazioni

Acrylamide has been used for preparing slab gel gradients for polyacrylamide gel electrophoresis (PAGE).

Azioni biochim/fisiol

Acrylamide is a reactive, water soluble vinyl monomer. It causes a decrease in the number of neuritis per cell as well as reduces the rate of protein synthesis.

Pittogrammi

Skull and crossbonesHealth hazard
GHS06,GHS08

Avvertenze

Danger

Classi di pericolo

Acute Tox. 3 Oral - Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Carc. 1B - Eye Irrit. 2 - Muta. 1B - Repr. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT RE 1 Oral

Organi bersaglio

Peripheral nervous system

Codice della classe di stoccaggio

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

280.4 °F - closed cup

Punto d’infiammabilità (°C)

138 °C - closed cup

Dispositivi di protezione individuale

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

Choose from one of the most recent versions:

Certificati d'analisi (COA)

Lot/Batch Number
BCCM2995
BCCL7033
BCCK3678
BCCH3077
BCCF6792

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Sigma-Aldrich

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Sigma-Aldrich

SAB4503853

Anti-phospho-Akt (pSer124) antibody produced in rabbit

M W Cunningham et al.
The Journal of experimental medicine, 164(4), 998-1012 (1986-10-01)
mAbs produced by immunization of BALB/c mice with Streptococcus pyogenes M type 5 membranes were further characterized for their reaction with S. pyogenes pep M5 protein and with autoantigens associated with human cell lines. mAbs 36.2.2 and 54.2.8 simultaneously reacted
M Nordin-Andersson et al.
Cell biology and toxicology, 19(1), 43-51 (2003-03-29)
Basal cytotoxicity, morphological changes and alterations in cell physiological and neurochemical functions were studied in differentiated human neuroblastoma (SH-SY5Y) cells during exposure to acrylamide and during a subsequent recovery period after cessation of exposure. Acrylamide induced a 20% reduction in
Rusty L Montgomery et al.
EMBO molecular medicine, 6(10), 1347-1356 (2014-09-23)
Over the last decade, great enthusiasm has evolved for microRNA (miRNA) therapeutics. Part of the excitement stems from the fact that a miRNA often regulates numerous related mRNAs. As such, modulation of a single miRNA allows for parallel regulation of
Janneke G F Hogervorst et al.
Carcinogenesis, 35(5), 1032-1038 (2014-01-09)
Acrylamide, a probable human carcinogen, is present in heat-treated carbohydrate-rich foods. Epidemiological studies have not shown a clear association between acrylamide intake and colorectal cancer (CRC) risk. This may be due to the molecular heterogeneity in colorectal tumors, which was
Franco Pedreschi et al.
Journal of the science of food and agriculture, 94(1), 9-20 (2013-08-14)
Acrylamide (AA) is known as a neurotoxin in humans and it is classified as a probable human carcinogen by the International Agency of Research on Cancer. AA is produced as by-product of the Maillard reaction in starchy foods processed at
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