HIFN-130K

MILLIPLEX^® Human Interferon Panel

• Codice UNSPSC: 12161503
• NACRES: NA.77

Proprietà

• impiego: kit sufficient for 96 wells
• Livello qualitativo: 200
• Reattività contro le specie: human
• Parametri: 25 μL sample volume (per well)
• tecniche: multiplexing: suitable
• Metodo di rivelazione: fluorometric (Luminex^® xMAP^®)
• Condizioni di spedizione: wet ice
• Temperatura di conservazione: 2-8°C

Descrizione

Descrizione generale

Interferons (IFNs) are widely expressed cytokines that have potent antiviral and antiproliferative effects. These cytokines are the first line of defense against viral infections and have important roles in immunosurveillance for malignant cells. IFNs are classified as type I, II and III IFNs, based upon the target receptors to which they bind. In humans, type I IFNs belong to a multigene family consisting of multiple IFNα subtypes but only one IFNβ, IFNε, IFNκ, and IFNω. There is only one type II IFN: IFNγ. The type III IFNs include IFNλ1, λ2 and λ3, which are also known as interleukin-29 (IL-29), IL 28A and IL-28B, respectively. Functionally, the type I and type III IFNs are induced during a viral infection and involved in host defense against viruses. IFNγ (type II) is primarily involved in the allergic response, in host defense against intracellular pathogens, and in control of tumor growth. Studies of IFNs have broadened the mechanistic understanding of cell signaling, gene transcription, and innate and acquired immunity.

Research category: Inflammation & ImmunologyResearch sub-category:

• Inflammation & Autoimmune Mechanisms
• Inflammation

Specificità

There was no or negligible cross-reactivity between the antibodies for an analyte and any of the other analytes in this panel.

Applicazioni

The MILLIPLEX^® Human Interferon Magnetic Bead Panel is a 9-plex kit to be used for the simultaneous quantification of any or all of the following analytes in serum or plasma samples and tissue/cell lysate and culture supernatant samples: IFNα-2, IFNβ, IFNε, IFNɣ, IFNɣ Receptor 1, IFNλ1, IFNλ2, IFNλ3, IFNω.

Caratteristiche e vantaggi

Design your multiplex kit by choosing available analytes within this panel.

Note legali

Luminex is a registered trademark of Luminex Corp

MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany

xMAP is a registered trademark of Luminex Corp

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informazioni sulla sicurezza

• Pittogrammi: GHS06,GHS08,GHS05,GHS09
• Avvertenze: Danger
• Indicazioni di pericolo: H302 + H332,H311,H317,H318,H373,H411
• Consigli di prudenza: P273 - P280 - P302 + P352 + P312 - P304 + P340 + P312 - P305 + P351 + P338 - P314
• Classi di pericolo: Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Sens. 1 - STOT RE 2
• Organi bersaglio: Respiratory Tract
• Codice della classe di stoccaggio: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects