ABN333

Anti-Neurotrypsin Antibody

from rabbit, purified by affinity chromatography

• Sinonimo/i: Neurotrypsin, Leydin, Motopsin, Serine protease 12
• Codice UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Proprietà

• Origine biologica: rabbit
• Livello qualitativo: 300
• Forma dell’anticorpo: affinity isolated antibody
• Tipo di anticorpo: primary antibodies
• Clone: polyclonal
• Purificato mediante: affinity chromatography
• Reattività contro le specie: mouse, human, rat
• tecniche: immunohistochemistry: suitable; western blot: suitable
• N° accesso UniProt: P56730
• Condizioni di spedizione: wet ice
• modifica post-traduzionali bersaglio: unmodified

Descrizione

Descrizione generale

Neurotrypsin is a central nervous system-expressed serine protease whose truncation or absence causes nonsyndromic mental retardation. It is most prominently expressed in structures that are involved in the processing and storage of learned behavior and memory, such as the cerebral cortex, the hippocampus, and amygdala. Evidence suggests that neurotrypsin has multiple functions. These functions include axonal outgrowth, maintaining neuronal plasticity, and arranging the perineuronal environment, partly in coordination with other proteases including tissue plasminogen activator. At least two isoforms of neurotrypsin are known to exist.

Immunogeno

KLH-conjugated linear peptide corresponding to human Neurotrypsin.

Applicazioni

Detect the Neurotrypsin protein using this Anti-Neurotrypsin validated for use in WB & IHC.

Western Blot Analysis: 1 µg/mL from a representative lot detected Neurotrypsin in 10 µg/mL of rat testis tissue lysate.

Immunohistochemistry Analysis: A 1:2,000 dilution from a representative lot detected Neurotrypsin in human midbrain and rat cerebellum tissues.

Qualità

Evaluated by Western Blot in mouse testis tissue lysate.

Western Blot Analysis: 1 µg/mL of this antibody detected Neurotrypsin in 10 µg/mL of mouse testis tissue lysate.

Descrizione del bersaglio

~97 kDa observed. Uncharacterized bands may appear at ~13 kDa, ~38 kDa, and ~43 kDa in some lysates.

Altre note

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 12 - Non Combustible Liquids
• Classe di pericolosità dell'acqua (WGK): WGK 2
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable