AB9906
Anti-QKI-6 Antibody
serum, Chemicon®
Sinonimo/i:
Quaking Protein
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About This Item
Codice UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Prodotti consigliati
Origine biologica
rabbit
Livello qualitativo
Forma dell’anticorpo
serum
Tipo di anticorpo
primary antibodies
Clone
polyclonal
Reattività contro le specie
mouse, rat, human
Produttore/marchio commerciale
Chemicon®
tecniche
immunoprecipitation (IP): suitable
western blot: suitable
N° accesso NCBI
N° accesso UniProt
Condizioni di spedizione
wet ice
modifica post-traduzionali bersaglio
unmodified
Informazioni sul gene
human ... QKI(9444)
Descrizione generale
QKI is an RNA-binding protein that plays a central role in myelinization. Acts by regulating pre-mRNA splicing, mRNA export, mRNA stability and protein translation. It is regulated by alternative splicing.
Specificità
QKI-6 (Quaking Protein). The antibody recognizes the ~38 kDa protein.
Immunogeno
Synthetic peptide from mouse QKI-6.
Applicazioni
Anti-QKI-6 Antibody detects level of QKI-6 & has been published & validated for use in IP & WB.
Research Category
Neuroscience
Neuroscience
Research Sub Category
Developmental Neuroscience
RNA Binding Protein (RBP)
Developmental Neuroscience
RNA Binding Protein (RBP)
Stato fisico
Liquid.
Serum
Stoccaggio e stabilità
Maintain at -20°C in undiluted aliquots for up to 12 months after date of receipt. Avoid repeated freeze/thaw cycles.
Risultati analitici
Control
Positive Control: Glial cells, astrocytes and oligodendrocytes.
Positive Control: Glial cells, astrocytes and oligodendrocytes.
Note legali
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Esclusione di responsabilità
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Codice della classe di stoccaggio
10 - Combustible liquids
Classe di pericolosità dell'acqua (WGK)
WGK 1
Punto d’infiammabilità (°F)
Not applicable
Punto d’infiammabilità (°C)
Not applicable
Certificati d'analisi (COA)
Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.
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I documenti relativi ai prodotti acquistati recentemente sono disponibili nell’Archivio dei documenti.
Zhengyi Zhang et al.
Nature communications, 10(1), 4397-4397 (2019-09-29)
Strand-selection is the final step of microRNA biogenesis in which functional mature miRNAs are generated from one or both arms of precursor. The preference of strand-selection is diverse during development and tissue formation, however, its pathological effect is still unknown.
Zhejia Zhang et al.
Oncology letters, 15(4), 5841-5848 (2018-03-21)
Thyroid cancer is the most frequently occurring type of endocrine tumor, with a rapidly increasing incidence rate. MicroRNA (miR)-574-5p is a candidate oncogene in various types of cancer. The present study identified that miR-574-5p affected the cell cycle distribution and
Kristina Sakers et al.
Nature communications, 12(1), 1537-1537 (2021-03-23)
Quaking RNA binding protein (QKI) is essential for oligodendrocyte development as myelination requires myelin basic protein mRNA regulation and localization by the cytoplasmic isoforms (e.g., QKI-6). QKI-6 is also highly expressed in astrocytes, which were recently demonstrated to have regulated
Claudia Dominici et al.
Life science alliance, 5(5) (2022-02-16)
Muscle stem cells (MuSCs) have the ability to carry out the specialized function of cell polarization, which is required for the production of one repopulating cell and one myogenic progenitor cell with muscle regeneration capabilities. The mechanisms which regulate proteins
Ruben G de Bruin et al.
Epigenomes, 4(1) (2020-02-13)
In the pathophysiologic setting of acute and chronic kidney injury, the excessive activation and recruitment of blood-borne monocytes prompts their differentiation into inflammatory macrophages, a process that leads to progressive glomerulosclerosis and interstitial fibrosis. Importantly, this differentiation of monocytes into
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