Passa al contenuto
Merck
Tutte le immagini(1)

Documenti

AB9682

Sigma-Aldrich

Anti-Dardarin Antibody

serum, Chemicon®

Sinonimo/i:

LRRK2 Leucine-rich repeat kinase 2

Autenticatiper visualizzare i prezzi riservati alla tua organizzazione & contrattuali


About This Item

Codice UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41

Origine biologica

rabbit

Livello qualitativo

Forma dell’anticorpo

serum

Tipo di anticorpo

primary antibodies

Clone

polyclonal

Reattività contro le specie

mouse, human

Produttore/marchio commerciale

Chemicon®

tecniche

ELISA: suitable
western blot: suitable

Isotipo

IgG

N° accesso NCBI

N° accesso UniProt

Condizioni di spedizione

dry ice

modifica post-traduzionali bersaglio

unmodified

Informazioni sul gene

human ... LRRK2(120892)

Specificità

Recognizes LRRK2 [leucine-rich repeat kinase 2, Dardarin]. By Western blot the antibody recognizes a band at ~240 kDa in mouse brain extract. An additional band at ~130-140 kDa can also be seen. On human brain lysate the antibody recognizes a band at ~150 kDa.

Immunogeno

Synthetic peptide from rat LRRK2.

Applicazioni

Anti-Dardarin Antibody detects level of Dardarin & has been published & validated for use in ELISA & WB.
Research Category
Neuroscience
Research Sub Category
Neurodegenerative Diseases
Western blot: 1:5,000-1:10,000 on mouse brain extract.

Optimal working dilutions must be determined by the end user.

Descrizione del bersaglio

286 kDa

Stato fisico

Rabbit Serum. Liquid.
Unpurified

Stoccaggio e stabilità

Maintain for 1 year at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Risultati analitici

Control
Brain tissue

Altre note

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Note legali

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Not finding the right product?  

Try our Motore di ricerca dei prodotti.

Codice della classe di stoccaggio

10 - Combustible liquids

Classe di pericolosità dell'acqua (WGK)

WGK 1


Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

Possiedi già questo prodotto?

I documenti relativi ai prodotti acquistati recentemente sono disponibili nell’Archivio dei documenti.

Visita l’Archivio dei documenti

Izabella D Greene et al.
Journal of neuroscience research, 92(4), 506-516 (2014-01-01)
Mutations in the leucine-rich repeat kinase 2 (lrrk2) gene are the leading genetic cause of Parkinson's disease (PD). In characterizing the novel ROC domain mutant A1442P, we compared its steady-state protein levels, propensity to aggregate, and toxicity with the pathogenic
Berta Pons et al.
Oncology reports, 27(1), 225-231 (2011-09-17)
Translational control is a crucial component of cancer development and progression. Eukaryotic initiation factor (eIF) 4E mediates eIF4F association with the mRNA
Saskia Biskup et al.
BMC neuroscience, 8, 102-102 (2007-11-30)
Mutations within the leucine-rich repeat kinase 2 (LRRK2) gene account for a significant proportion of autosomal-dominant and some late-onset sporadic Parkinson's disease. Elucidation of LRRK2 protein function in health and disease provides an opportunity for deciphering molecular pathways important in

Il team dei nostri ricercatori vanta grande esperienza in tutte le aree della ricerca quali Life Science, scienza dei materiali, sintesi chimica, cromatografia, discipline analitiche, ecc..

Contatta l'Assistenza Tecnica.