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5.04359

Palmitoylethanolamide

Name: Palmitoylethanolamide
Brand: MM
Price: 136 CHF

Sinonimo/i:

Palmitoylethanolamide, N-(2-Hydroxyethyl)hexadecanamide, PEA, Palmidrol

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A voi/SKU	Disponibilità	Prezzo
10 mg	Per conoscere la disponibilità, visualizza il carrello	CHF 136.00

Informazioni su questo articolo

Formula empirica (notazione di Hill):

C₁₈H₃₇NO₂

Numero CAS:

544-31-0

Peso molecolare:

299.49

UNSPSC Code:

51111800

NACRES:

NA.77

MDL number:

MFCD00020562

Assay:

≥99% (HPLC)

Form:

solid

Storage condition:

OK to freeze, protect from light

CHF 136.00

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Proprietà

assay

≥99% (HPLC)

Quality Segment

100

form

solid

manufacturer/tradename

Calbiochem^®

storage condition

OK to freeze, protect from light

color

white

solubility

DMSO: 20 mM

storage temp.

−20°C

SMILES string

N(CCO)C(=O)CCCCCCCCCCCCCCC

InChI

1S/C18H37NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-18(21)19-16-17-20/h20H,2-17H2,1H3,(H,19,21)

InChI key

HXYVTAGFYLMHSO-UHFFFAOYSA-N

Descrizione

General description

An endogenous lipid that acts as a selective agonist for GPR55 receptors (EC₅₀ = 4, 19 800 and >30 000 nM at GPR55, CB₂ and CB₁ receptors respectively). Producing robust anti-inflammatory actions by activating PPARα (EC₅₀ = 3 µM).

Biochem/physiol Actions

Primary Target
GPR55 receptor

Preparation Note

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Slight warming is required for complete solubilization.

Other Notes

Griffin, G., et al. 2000. J. Pharmacol. Exp. Ther.292, 886.

Lambert, D., et al. 2001. Epilepsia.42, 321.
Lambert, D., et al. 2002. Curr. Med. Chem.9, 663.
Lo Verme, J., et al. 2005. Life Sci.77, 1685.
Re, G., et al. 2005. Vet. J.173, 21.
Ryberg, R., et al. 2007. Br. J. Pharmacol.152, 1092.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)

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Questo articolo	P0359	5.06045	370698
Sigma-Aldrich 5.04359 Palmitoylethanolamide	Sigma-Aldrich P0359 Palmitoylethanolamide	Sigma-Aldrich 5.06045 GPR55 Receptor Antagonist, CID16020046	Sigma-Aldrich 370698 GW7647
assay ≥99% (HPLC)	assay -	assay ≥99% (HPLC)	assay ≥98% (HPLC)
form solid	form powder	form powder	form solid
manufacturer/tradename Calbiochem^®	manufacturer/tradename -	manufacturer/tradename Calbiochem^®	manufacturer/tradename Calbiochem^®
Quality Level 100	Quality Level 200	Quality Level 100	Quality Level 100
storage temp. −20°C	storage temp. −20°C	storage temp. 2-8°C	storage temp. 2-8°C
solubility DMSO: 20 mM	solubility -	solubility DMSO: 100 mg/mL	solubility ethanol: 12 mg/mL, DMSO: 50 mg/mL

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pictograms

GHS05,GHS09

signalword

Danger

pcodes

P264 - P273 - P280 - P302 + P352 - P305 + P351 + P338 - P332 + P313

Hazard Classifications

Aquatic Chronic 2 - Eye Dam. 1 - Skin Irrit. 2

Classe di stoccaggio

13 - Non Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c