454428

4-Methylumbelliferyl-6-sulfo-N-acetyl-β-D-glucosaminide potassium salt

≥98% (HPLC), crystalline solid, hexosaminidase A substrate, Calbiochem^®

• Sinonimo/i: 4-Methylumbelliferyl-6-sulfo-N-acetyl-β-D-glucosaminide, Potassium Salt, 4-Methylumbelliferyl-6-sulfo-2-acetamido-2-deoxy-β-D-glucopyranoside, K
• Formula empirica (notazione di Hill): C₁₈H₂₀NO₁₁S · K
• Peso molecolare: 497.51
• UNSPSC Code: 51111800
• NACRES: NA.77
• Assay: ≥98% (HPLC)
• Form: crystalline solid
• Storage condition: OK to freeze, desiccated, protect from light

Proprietà

• Nome del prodotto: 4-Methylumbelliferyl-6-sulfo-N-acetyl-β-D-glucosaminide, Potassium Salt, Fluorogenic substrate for isoenzyme A of N-acetyl-β-D-glucosaminidase (hexosaminidase A). Can be used for the prenatal diagnosis of Tay-Sachs disease and for the classification of GM2 gangliosidosis genotypes.
• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: crystalline solid
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze, desiccated, protect from light
• color: white
• solubility: water: 20 mg/mL
• fluorescence: λ_ex 360 nm, λ_em 440 nm
• shipped in: ambient
• storage temp.: −20°C

Descrizione

General description

Fluorogenic substrate for isoenzyme A of N-acetyl-β-D-glucosaminidase (hexosaminidase A). Can be used for the prenatal diagnosis of Tay-Sachs disease and for the classification of GM₂ gangliosidosis genotypes. Excitation maximum: ~360 nm; emission maximum: ~440 nm.

Preparation Note

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.

Other Notes

Greloner, E.E., and Wenger, D.A. 1987. Prenat. Diag. 7, 419.
Bayleran, J., et al. 1984. Clin. Chim. Acta143, 73.
Inui, K., and Wenger, D.A. 1984. Clin. Genet.25, 93.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)

Informazioni sulla sicurezza

• Classe di stoccaggio: 11 - Combustible Solids
• wgk: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable