420123-M

JNK Inhibitor II, Negative Control

The JNK Inhibitor II, Negative Control, also referenced under CAS 54642-23-8, controls the biological activity of JNK. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.

• Sinonimo/i: JNK Inhibitor II, Negative Control, N¹-Methyl-1,9-pyrazoloanthrone
• Formula empirica (notazione di Hill): C₁₅H₁₀N₂O
• Numero CAS: 54642-23-8
• Peso molecolare: 234.25
• Codice UNSPSC: 12352200

Proprietà

• Livello qualitativo: 100
• Saggio: ≥97% (HPLC)
• Forma fisica: solid
• Produttore/marchio commerciale: Calbiochem^®
• Condizioni di stoccaggio: OK to freeze; protect from light
• Colore: yellow
• Solubilità: DMSO: 10 mg/mL
• Temperatura di conservazione: −20°C

Descrizione

Descrizione generale

A useful negative control for JNK Inhibitor II (SP600125, Cat. No. 420119). Inhibits JNK2 and JNK3 only at much higher concentrations (IC₅₀ = 18 µM and 24 µM, respectively) compared to SP600125 (IC₅₀ = 40 nM and 90 nM, respectively).

A useful negative control for JNK Inhibitor II (SP600125, Cat. No. 420119). Inhibits JNK2 and JNK3 only at much higher concentrations (IC₅₀ = 18 µM and 24 µM, respectively) compared to SP600125 (IC₅₀ = 40 nM and 90 nM, respectively).

Azioni biochim/fisiol

Primary Target
A useful negative control for JNK Inhibitor II (SP600125, Cat. No. 420119)

Target IC₅₀: 18 µM and 24 µM against JNK2 and JNK3, respectively

Attenzione

Toxicity: Standard Handling (A)

Ricostituzione

Following reconstitution aliquot and freeze (-20°C). Stock solutions are stable up to 3 months at -20°C.

Altre note

Shin, M., and Boyd, Y.D. 2002. Biochim. Biophys. Acta1589, 311.
Bennett, B.L., et al. 2001. Proc. Natl. Acad. Sci. USA98, 13681.

Note legali

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 1
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable