362338

Glyco-SNAP-1 - Calbiochem

A water-soluble nitric oxide (NO) donor.

• Sinonimo/i: Glyco-SNAP-1 - Calbiochem, N-(β-D-Glucopyranosyl)-N²-acetyl-S-nitroso-D,L-penicillaminamide
• Formula empirica (notazione di Hill): C₁₃H₂₃N₃O₈S
• Peso molecolare: 381.40
• Codice UNSPSC: 12352200

Proprietà

• Livello qualitativo: 100
• Saggio: ≥96% (NMR)
• Stato: crystalline solid
• Produttore/marchio commerciale: Calbiochem^®
• Condizioni di stoccaggio: OK to freeze; protect from light
• Colore: green
• Solubilità: aqueous buffer: 100 mg/mL; water: 100 mg/mL; methanol: 5 mg/mL
• Condizioni di spedizione: ambient
• Temperatura di conservazione: −20°C

Descrizione

Descrizione generale

A water-soluble and stable nitric oxide (NO) donor (t_½ = 28.5-30.2 hr). Glyco-SNAP-1 is more stable than SNAP (Cat. No. 487910) in aqueous solution with or without EDTA and is relatively stable at high pH (pH 8-9). The SNAP moiety acts as an NO group donor and the sugar fragment provides hydrophilicity and specificity. Compared to SNAP, glyco-SNAP-1 decomposes much more slowly in the presence of thiols such as cysteine or glutathione.

A water-soluble nitric oxide (NO) donor. More stable (t_½ = 28.5-30.2 hr) than SNAP (Cat. No. 487910) in aqueous solution with or without EDTA and is relatively stable at high pH (pH 8 - 9). The SNAP moiety acts as an NO group donor and the sugar moiety provides hydrophilicity and specificity. Compared to SNAP, glyco-SNAP-1 decomposes at a much slower rate in the presence of thiols such as cysteine or glutathione.

Azioni biochim/fisiol

Cell permeable: no

Primary Target
A water-soluble nitric oxide (NO) donor

Product does not compete with ATP.

Reversible: no

Attenzione

Toxicity: Standard Handling (A)

Ricostituzione

Unstable in solution; reconstitute just prior to use.

Altre note

Hou, Y., et al. 1999. Methods Enzymol. 301, 242.
Ramirez, J., et al. 1996. Bioorg. Med. Chem. Lett.6, 2575.

Note legali

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 1
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable