344038

cFMS Receptor Inhibitor III - CAS 959861-21-3 - Calbiochem

• Sinonimo/i: cFMS Receptor Inhibitor III - CAS 959861-21-3 - Calbiochem, 4-(3,4-Dimethylanilino)-7-(4-(methylsulfonyl)phenyl)quinoline-3-carboxamide, CSF-1 Receptor Inhibitor III
• Formula empirica (notazione di Hill): C₂₅H₂₃N₃O₃S
• Numero CAS: 959861-21-3
• Peso molecolare: 445.53
• Codice UNSPSC: 12352200

Proprietà

• Saggio: ≥97% (HPLC)
• Livello qualitativo: 100
• Forma fisica: solid
• Produttore/marchio commerciale: Calbiochem^®
• Condizioni di stoccaggio: OK to freeze; protect from light
• Colore: yellow
• Solubilità: DMSO: 100 mg/mL
• Condizioni di spedizione: ambient
• Temperatura di conservazione: 2-8°C

Descrizione

Descrizione generale

This product has been discontinued.

A cell-permeable anilinoquinoline compound that acts as a potent, active site-targeting inhibitor of MCSF receptor/cFMS (IC₅₀ = 8 nM). It is 100-fold more potent in inhibiting the cFMS-dependent growth of M-NSF-60 cells than the cFMS-independent growth of NSO cells (IC₅₀ = 0.1 and 10 µM, respectively).

A cell-permeable anilinoquinoline compound that acts as a potent, active site-targeting inhibitor of MCSF receptor/cFMS (IC₅₀ = 8 nM). It is 100-fold more potent in inhibiting the cFMS-dependent growth of M-NSF-60 cells than the cFMS-independent growth of NSO cells (IC₅₀ = 0.1 and 10 µM, respectively).

Confezionamento

Packaged under inert gas

Attenzione

Toxicity: Standard Handling (A)

Ricostituzione

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.

Altre note

Smalley, T.L. Jr., et al. 2007. Bioorg. Med. Chem. Lett.17, 6257.

Note legali

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 10-13 - German Storage Class 10 to 13