20-107

Peroxynitrite

• UNSPSC Code: 41116012
• NACRES: NA.41
• eCl@ss: 32160405
• Form: liquid

Proprietà

• form: liquid
• Quality Segment: 100
• manufacturer/tradename: Upstate^®
• technique(s): western blot: suitable
• shipped in: dry ice

Descrizione

General description

Peroxynitrite (ONOO−) is a powerful oxidant formed by the collision of nitric oxide and superoxide.

Application

Peroxynitrite has been used to induce pericyte contraction in mouse brains. It has also been used for the preparation of positive control nitrated protein standards in immunohistochemical studies.

Biochem/physiol Actions

Peroxynitrite (ONOO−) exhibits bactericidal activity. It promotes cell death and contributes to the signal-transduction process, mitochondrial function, and apoptotic pathway. The formation of peroxynitrite has been associated with the development of various diseases including vascular diseases, ischemia-reperfusion injury, circulatory shock, inflammation, pain, and neurodegeneration.

Physical form

0.3M NaOH

Analysis Note

Routinely evaluated by treating non-stimulated A431 cells.

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Informazioni sulla sicurezza

• pictograms: GHS05
• signalword: Warning
• hcodes: H290,H315,H319
• pcodes: P234 - P264 - P280 - P302 + P352 - P305 + P351 + P338 - P332 + P313
• Hazard Classifications: Eye Irrit. 2 - Met. Corr. 1 - Skin Irrit. 2
• Classe di stoccaggio: 12 - Non Combustible Liquids