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Sigma-Aldrich

Anti-acetyl Lysine Antibody, clone 4G12, agarose conjugate

clone 4G12, Upstate®, from mouse

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100 μG
CHF 543.00

CHF 543.00


Spedizione prevista il17 maggio 2025



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Cambia visualizzazione
100 μG
CHF 543.00

About This Item

Codice UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41

CHF 543.00


Spedizione prevista il17 maggio 2025


Origine biologica

mouse

Livello qualitativo

Forma dell’anticorpo

purified antibody

Tipo di anticorpo

primary antibodies

Clone

4G12, monoclonal

Reattività contro le specie (prevista in base all’omologia)

all

Produttore/marchio commerciale

Upstate®

tecniche

immunoprecipitation (IP): suitable

Condizioni di spedizione

wet ice

modifica post-traduzionali bersaglio

acetylation (Lys)

Specificità

Recognizes acetyl lysine-containing proteins including histones.

Immunogeno

A mixture of chemically acetylated antigens. Clone 4G12.

Applicazioni

Detect acetyl Lysine with Anti-acetyl Lysine Antibody, clone 4G12, agarose conjugate (Mouse Monoclonal Antibody), that has been shown to work in IP.
Research Category
Signaling

Epigenetics & Nuclear Function
Research Sub Category
General Post-translation Modification

Histones

Caratteristiche e vantaggi

Format: Gel Immobilized

Qualità

Routinely evaluated by immunoprecipitating

Descrizione del bersaglio

varies depending upon the protein being detected

Stoccaggio e stabilità

1 year at 4°C from date of shipment. DO NOT FREEZE.

Altre note

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Note legali

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Codice della classe di stoccaggio

12 - Non Combustible Liquids

Classe di pericolosità dell'acqua (WGK)

WGK 2

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable


Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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Yan Liu et al.
Journal of proteome research, 20(5), 2596-2606 (2021-04-02)
Decreased cellular NAD+ levels are causally linked to aging and aging-associated diseases. NAD+ precursors in oxidized form such as nicotinamide mononucleotide (NMN) and nicotinamide riboside (NR) have gained much attention and been well studied for their ability to restore NAD+
A Villagra et al.
Methods in enzymology, 573, 161-181 (2016-07-04)
Histone deacetylase assays were first developed in the 1970s, and subsequently refined in the 1990s with the cloning of HDAC enzymes. Most of these early assays, relying on traditional in vitro chemical methodologies, are still applicable today. More recently, however
N Munshi et al.
Molecular cell, 2(4), 457-467 (1998-11-11)
The transcriptional coactivators CBP and P/CAF are required for activation of transcription from the IFN beta enhanceosome. We show that CBP and P/CAF acetylate HMG I(Y), the essential architectural component required for enhanceosome assembly, at distinct lysine residues, causing distinct
Acetylation of general transcription factors by histone acetyltransferases.
Imhof, A, et al.
Current Biology, 7, 689-692 (1997)
Fei Yue et al.
Aging, 7(10), 839-853 (2015-11-06)
Autophagy controls and executes the turnover of abnormally aggregated proteins. MAP1S interacts with the autophagy marker LC3 and positively regulates autophagy flux. HDAC4 associates with the aggregation-prone mutant huntingtin protein (mHTT) that causes Huntington's disease, and colocalizes with it in

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