14-818-M

Met (D1246N) Protein, active, 10 µg

Active, N-terminal 6His-tagged, recombinant, human, Met amino acids 974-end, containing the mutation D1246N, for use in Kinase Assays.

• Codice UNSPSC: 12352202
• eCl@ss: 32160405
• NACRES: NA.32

Proprietà

• Origine biologica: human
• Livello qualitativo: 300
• Ricombinante: expressed in Sf21 cells
• PM: M_w 50.1 kDa
• Produttore/marchio commerciale: Upstate^®
• tecniche: activity assay: suitable (kinase)
• N° accesso UniProt: J02958; P08581

Descrizione

Descrizione generale

Met D1246N is a germline mutation that has been identified in patients with hereditary papillary renal carcinomas (HPRC). In vitro studies have demonstrated enhanced kinase activity from this mutant.

N-terminal 6His-tagged, recombinant, human, Met amino acids 974-end, containing the mutation D1246N

Product Source: expressed by baculovirus in Sf21 insect cells

Azioni biochim/fisiol

Protein Target: Met

Target Sub-Family: TK

Confezionamento

Available in 250 μg --call for pricing and availability and reference catalog number 14-818M when ordering the 250 μg size.

Stato fisico

Ni²⁺/NTA-agarose

Stoccaggio e stabilità

6 months at -70°C

Altre note

For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.

Note legali

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informazioni sulla sicurezza

• Pittogrammi: GHS07
• Avvertenze: Warning
• Indicazioni di pericolo: H317
• Consigli di prudenza: P261 - P272 - P280 - P302 + P352 - P333 + P313 - P362 + P364
• Classi di pericolo: Skin Sens. 1
• Codice della classe di stoccaggio: 12 - Non Combustible Liquids
• Classe di pericolosità dell'acqua (WGK): WGK 2
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable