14-687-M

p38α/SAPK2a (T106M) Protein, active, 10 µg

Active, N-terminal GST-tagged, recombinant, human, full-length p38α/SAPK2a containing the mutation T106M. Activated using DD-MKK6 & repurified using glutathione-agarose. For use in Kinase Assays.

• Codice UNSPSC: 12352202
• eCl@ss: 32160405
• NACRES: NA.32

Proprietà

• Origine biologica: human
• Livello qualitativo: 100; 300
• Ricombinante: expressed in E. coli
• PM: M_w 67.7 kDa
• Produttore/marchio commerciale: Upstate^®
• tecniche: activity assay: suitable (kinase)
• N° accesso NCBI: NM_001315.1; NM_139012.1; NM_139013.1; NM_139014.1
• N° accesso UniProt: Q16539
• Informazioni sul gene: human ... MAPK14(1432)

Descrizione

Descrizione generale

N-terminal GST-tagged, recombinant, human, full-length p38α/SAPK2a containing the mutation T106M. Activated using DD-MKK6 (14-537) and repurified using glutathione- agarose.

Contains the gatekeeper mutation T160M in the ATP-binding domain. This mutation increases resistance to SB203580 as compared to the wild type sequence.

Product Source: Human, full-length p38α/SAPK2a containing the mutation T106M. Expressed in E. coli.

Qualità

routinely evaluated by phosphorylation of MBP (13-104).

Altre note

For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.

Note legali

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Informazioni sulla sicurezza

• Pittogrammi: GHS07
• Avvertenze: Warning
• Indicazioni di pericolo: H317
• Consigli di prudenza: P261 - P272 - P280 - P302 + P352 - P333 + P313 - P362 + P364
• Classi di pericolo: Skin Sens. 1
• Codice della classe di stoccaggio: 10 - Combustible liquids
• Classe di pericolosità dell'acqua (WGK): WGK 2