07-550
Anti-SUV39H1 Antibody
Upstate®, from rabbit
Sinonimo/i:
KMT1A
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About This Item
Codice UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Origine biologica
rabbit
Forma dell’anticorpo
purified antibody
Tipo di anticorpo
primary antibodies
Clone
polyclonal
Reattività contro le specie
human, mouse
Produttore/marchio commerciale
Upstate®
tecniche
western blot: suitable
Isotipo
IgG
N° accesso UniProt
Condizioni di spedizione
wet ice
modifica post-traduzionali bersaglio
unmodified
Informazioni sul gene
human ... SUV39H1(6839)
Specificità
SUV39H1
Immunogeno
Peptide (C-QVDPVDMESTRMDSNFGLAGLPGSP) corresponding to amino acids 368-392 of mouse suppressor of variegation 3-9 homolog 1 (SUV39H1).
Applicazioni
Research Category
Epigenetics & Nuclear Function
Epigenetics & Nuclear Function
Research Sub Category
Histones
Histones
Use Anti-SUV39H1 Antibody (Rabbit Polyclonal Antibody) validated in WB to detect SUV39H1 also known as KMT1A, Histone H3-K9 Methyltransferase 1.
Qualità
Routinely evaluated by immunoblot in U20S cells lysed in RIPA with 0.1% SDS and sonicated.
Descrizione del bersaglio
48kDa
Linkage
Replaces: MABE552
Stato fisico
0.1M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide, pH 7.4.
Format: Purified
Protein A purified
Stoccaggio e stabilità
Stable for 1 year at 2-8°C from date of receipt.
For maximum recovery of product, centrifuge the vial prior to removing the cap.
For maximum recovery of product, centrifuge the vial prior to removing the cap.
Note legali
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Esclusione di responsabilità
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Codice della classe di stoccaggio
10 - Combustible liquids
Classe di pericolosità dell'acqua (WGK)
WGK 1
Certificati d'analisi (COA)
Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.
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I documenti relativi ai prodotti acquistati recentemente sono disponibili nell’Archivio dei documenti.
Hakima Yahi et al.
The Journal of biological chemistry, 283(35), 23692-23700 (2008-07-05)
Mechanisms of transcriptional repression are important during cell differentiation. Mammalian heterochromatin protein 1 isoforms HP1alpha, HP1beta, and HP1gamma play important roles in the regulation of chromatin structure and function. We explored the possibility of different roles for the three HP1
S J Nielsen et al.
Nature, 412(6846), 561-565 (2001-08-03)
In eukaryotic cells the histone methylase SUV39H1 and the methyl-lysine binding protein HP1 functionally interact to repress transcription at heterochromatic sites. Lysine 9 of histone H3 is methylated by SUV39H1 (ref. 2), creating a binding site for the chromo domain
R Firestein et al.
Molecular and cellular biology, 20(13), 4900-4909 (2000-06-10)
Mammalian SET domain-containing proteins define a distinctive class of chromatin-associated factors that are targets for growth control signals and oncogenic activation. SUV39H1, a mammalian ortholog of Drosophila Su(var)3-9, contains both SET and chromo domains, signature motifs for proteins that contribute
Imtiyaz Yaseen et al.
The EMBO journal, 37(2), 183-200 (2017-11-25)
Host cell defense against an invading pathogen depends upon various multifactorial mechanisms, several of which remain undiscovered. Here, we report a novel defense mechanism against mycobacterial infection that utilizes the histone methyltransferase, SUV39H1. Normally, a part of the host chromatin
Rajeev Mishra et al.
3 Biotech, 12(11), 290-290 (2022-10-25)
Telomere length is primarily controlled by the enzyme telomerase, but being chromatin structures, telomeres undergo epigenetic regulation for their maintenance and function. Altered telomere length among cancer cells combined with shorter telomere length in cancer-associated stromal cells, strongly implicated with
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