05-435
Anti-Lck Antibody, clone 3A5
clone 3A5, Upstate®, from mouse
Sinonimo/i:
Anti-IMD22, Anti-LSK, Anti-YT16, Anti-p56lck, Anti-pp58lck
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About This Item
Codice UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Origine biologica
mouse
Livello qualitativo
Forma dell’anticorpo
purified immunoglobulin
Tipo di anticorpo
primary antibodies
Clone
3A5, monoclonal
Reattività contro le specie
mouse, human, rat
Produttore/marchio commerciale
Upstate®
tecniche
immunoprecipitation (IP): suitable
western blot: suitable
Isotipo
IgG2bκ
N° accesso NCBI
N° accesso UniProt
Condizioni di spedizione
dry ice
modifica post-traduzionali bersaglio
unmodified
Informazioni sul gene
human ... LCK(3932)
Specificità
Recognizes Lck.
Immunogeno
GST-fusion to residues 1-225 of murine Lck
Applicazioni
Research Category
Signaling
Signaling
Research Sub Category
Immunological Signaling
Immunological Signaling
This Anti-Lck Antibody, clone 3A5 is validated for use in IP, WB for the detection of Lck.
Qualità
routinely evaluated by immunoblot on RIPA lysates from Jurkat cells
Descrizione del bersaglio
56 kDa
Linkage
Replaces: 04-372
Stato fisico
Format: Purified
Protein A purified
Protein A purified antibody in 100uL of 10mM PBS, pH 7.4
Stoccaggio e stabilità
Maintain for 2 years at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Risultati analitici
Control
Positive Antigen Control: Catalog #12-303, Jurkat cell lysate.
Positive Antigen Control: Catalog #12-303, Jurkat cell lysate.
Altre note
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Note legali
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Esclusione di responsabilità
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Codice della classe di stoccaggio
12 - Non Combustible Liquids
Classe di pericolosità dell'acqua (WGK)
WGK 2
Punto d’infiammabilità (°F)
Not applicable
Punto d’infiammabilità (°C)
Not applicable
Certificati d'analisi (COA)
Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.
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I documenti relativi ai prodotti acquistati recentemente sono disponibili nell’Archivio dei documenti.
The differential expression of LCK and BAFF-receptor and their role in apoptosis in human lymphomas.
Jennifer C Paterson, Sara Tedoldi, Andrew Craxton, Margaret Jones, Martin-Leo Hansmann et al.
Haematologica null
B Omri et al.
Journal of neurochemistry, 67(4), 1360-1364 (1996-10-01)
The lck gene product, p56lck, is a member of the src-related family of protein tyrosine kinases. It is known as lymphocyte specific and involved in thymocyte development and in the immune response mediated by the T cell receptor. We report
Association of SRC-related kinase Lyn with the interleukin-2 receptor and its role in maintaining constitutive phosphorylation of JAK/STAT in human T-cell leukemia virus type 1-transformed T cells.
Shuh, M; Morse, BA; Heidecker, G; Derse, D
Journal of virology null
Tiphaine Douanne et al.
Open biology, 14(2), 230456-230456 (2024-02-28)
Cytotoxic T lymphocytes (CTLs) are key effectors of the adaptive immune system that recognize and eliminate virally infected and cancerous cells. In naive CD8+ T cells, T-cell receptor (TCR) engagement drives a number of transcriptional, translational and proliferation changes over
Jing Jin et al.
Molecular and cellular biology, 36(6), 1007-1018 (2016-01-13)
The heat shock protein 90 (HSP90) and cell division cycle 37 (CDC37) chaperones are key regulators of protein kinase folding and maturation. Recent evidence suggests that thermodynamic properties of kinases, rather than primary sequences, are recognized by the chaperones. In
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Contatta l'Assistenza Tecnica.