C-121

Carbamazepine-10,11-epoxide solution

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant^®

• Formula empirica (notazione di Hill): C₁₅H₁₂N₂O₂
• Numero CAS: 36507-30-9
• Peso molecolare: 252.27
• NACRES: NA.24
• PubChem Substance ID: 329774876
• UNSPSC Code: 41116107
• EC Number: 200-659-6
• MDL number: MFCD00467137
• eCl@ss: 25140904

Proprietà

• grade: certified reference material
• Quality Segment: 300
• form: liquid
• feature: Snap-N-Spike^®/Snap-N-Shoot^®
• packaging: ampule of 1 mL
• manufacturer/tradename: Cerilliant^®
• concentration: 1.0 mg/mL in methanol
• technique(s): gas chromatography (GC): suitable, liquid chromatography (LC): suitable
• application(s): clinical testing
• format: single component solution
• storage temp.: −20°C
• SMILES string: O=C(N)N1C2=CC=CC=C2C3C(O3)C4=CC=CC=C14
• InChI: 1S/C15H12N2O2/c16-15(18)17-11-7-3-1-5-9(11)13-14(19-13)10-6-2-4-8-12(10)17/h1-8,13-14H,(H2,16,18)
• InChI key: ZRWWEEVEIOGMMT-UHFFFAOYSA-N

Descrizione

General description

Carbamazepine-10,11-epoxide is the primary, active metabolite in both urine and serum of carbamazepine, an anticonvulsant drug used in the treatment of epilepsy and bipolar disorder as well as trigeminal neuralgia. Potential toxicity of the epoxide metabolite requires regular therapeutic drug monitoring by LC or LC/MS for patients taking carbamazepine.

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Supply conditions do not apply to the regions and states of Brazil: North, Northeast, Mato Grosso do Sul, Mato Grosso, and Rio Grande do Sul.

Informazioni sulla sicurezza

• Pittogrammi: GHS02,GHS06,GHS08
• Parola di avvertenza: Danger
• Codici di pericolo: H225,H301 + H311 + H331,H370
• Avvertenze di sicurezza: P210 - P280 - P301 + P310 + P330 - P302 + P352 + P312 - P304 + P340 + P311
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• Organi bersaglio: Eyes
• Classe di stoccaggio: 3 - Flammable liquids
• Che succede?: WGK 1
• Punto di infiammabilità (°F): 49.5 °F - closed cup
• Punto di infiammabilità (°C): 9.7 °C - closed cup