B-052

(±)-Bupropion-D₉ hydrochloride solution

100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant^®

• Formula empirica (notazione di Hill): C₁₃H₉D₉ClNO · HCl
• Numero CAS: 1189725-26-5
• Peso molecolare: 285.26
• Numero CE: 200-659-6
• Numero MDL: MFCD08063410
• Codice UNSPSC: 41116107
• ID PubChem: 329773116
• NACRES: NA.24

Proprietà

• Grado: certified reference material
• Forma fisica: liquid
• Caratteristiche: (Snap-N-Spike^®)
• Confezionamento: ampule of 1 mL
• Produttore/marchio commerciale: Cerilliant^®
• Concentrazione: 100 μg/mL in methanol
• tecniche: gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• applicazioni: clinical testing
• Formato: single component solution
• Temperatura di conservazione: −20°C
• Stringa SMILE: CC(NC(C([2H])([2H])[2H])(C([2H])([2H])[2H])C([2H])([2H])[2H])C(C1=CC=CC(Cl)=C1)=O.Cl
• InChI: 1S/C13H18ClNO.ClH/c1-9(15-13(2,3)4)12(16)10-6-5-7-11(14)8-10;/h5-9,15H,1-4H3;1H/i2D3,3D3,4D3;; HEYVINCGKDONRU-WWMMTMLWSA-N

Descrizione

Descrizione generale

Bupropion is an antidepressant and smoking cessation drug sold under the trade names Wellbutrin^® and Zyban^®. Suitable uses for this certified solution standard include as an internal standard for quantitation of bupropion levels in biological matrices such as urine or isotope dilution methods by LC/MS or GC/MS for clinical toxicology, urine drug testing, or forensic analysis applications.

Applicazioni

• Pharmaceutical and nanotechnology applications: Bupropion-D9 hydrochloride is used in the development of UV-triggered drug release systems involving mesoporous titanium nanoparticles loaded with pharmaceutical agents, demonstrating its utility in enhancing drug delivery mechanisms and controlled release technologies (Zuo et al., 2024).
• Dermatological research: The solution is integral in evaluating antioxidant activities and the treatment of conditions such as eczema using berberine hydrochloride-loaded liposomes, highlighting its role in dermatological research and therapeutic applications (Shen et al., 2024).
• Cancer therapy: Utilized in the synthesis of small-molecule EGFR inhibitors for cancer therapy, Bupropion-D9 HCl serves as a stable isotope-labeled compound, crucial for understanding the pharmacokinetics and biochemical interactions of potential cancer treatments (Wang et al., 2024).
• Biomedical polymer research: The compound supports studies on the effects of various factors on poly(lactic-co-glycolic acid) nanoparticle properties, contributing to advancements in biodegradable polymer research for drug encapsulation and release behaviors (Wang et al., 2024).

Note legali

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Wellbutrin is a registered trademark of GlaxoSmithKline LLC

Zyban is a registered trademark of Everris International B.V.

Informazioni sulla sicurezza

• Pittogrammi: GHS02,GHS06,GHS08
• Avvertenze: Danger
• Indicazioni di pericolo: H225,H301 + H311 + H331,H370
• Consigli di prudenza: P210 - P280 - P301 + P310 + P330 - P302 + P352 + P312 - P304 + P340 + P311
• Classi di pericolo: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• Organi bersaglio: Eyes
• Codice della classe di stoccaggio: 3 - Flammable liquids
• Classe di pericolosità dell'acqua (WGK): WGK 1
• Punto d’infiammabilità (°F): 49.5 °F
• Punto d’infiammabilità (°C): 9.7 °C