QBD10722

Hydroxy-dPEG^®₂₄-t-butyl ester

>90% (HPLC)

• Sinonimo/i: HO-PEG₂₄-CO-Otbu, HO-PEG₂₄-TBE, Hydroxy-PEG-t-butyl ester, Hydroxy-PEG₂₄-t-butyl-ester, PEG₁₀₀₀-t-butyl ester
• Formula empirica (notazione di Hill): C₅₅H₁₁₀O₂₇
• Peso molecolare: 1203.45
• Numero MDL: MFCD13185018
• Codice UNSPSC: 12352108
• NACRES: NA.22

Proprietà

• Saggio: >90% (HPLC)
• Stato: solid or viscous liquid
• Impiego in reazioni chimiche: reaction type: Pegylations
• Architettura del polimero: shape: linear; functionality: heterobifunctional
• Condizioni di spedizione: ambient
• Temperatura di conservazione: −20°C
• Stringa SMILE: O(CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(=O)OC(C)(C)C)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCO
• InChI: YMILISGQCISYOH-UHFFFAOYSA-N

Descrizione

Caratteristiche e vantaggi

Hydroxy-dPEG₂₄-t-butyl ester is a versatile building block based upon a monodispersed polyethylene glycol (PEG) chain, comparable to a polymeric PEG₁₀₀₀. The single molecular weight, discrete-length PEG (dPEG) chain is 86 atoms (88.5 Å) long. A primary alcohol group terminates one end of the molecule. The opposite end is a propionic acid group protected as the tert-butyl ester. The terminal hydroxy group can be functionalized with various reactive groups to permit direct modification of surfaces, small molecules, or biomolecules. The tert-butyl ester deprotects with trifluoroacetic acid (TFA), exposing the terminal propionic acid, which can then be activated as the NHS or TFP ester or directly coupled to an amine using a suitable carbodiimide.

Note legali

Products Protected under U.S. Patent #s 7,888,536 & 8,637,711 and European Patent #s 1,594,440 & 2,750,681

dPEG is a registered trademark of Quanta BioDesign

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable