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Merck
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Documenti

96260

Sigma-Aldrich

Z-Gly-Phe

≥99.0%

Sinonimo/i:

Z-glycyl-L-phenylalanine

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About This Item

Formula condensata:
C6H5CH2OOCNHCH2CONHCH(CH2C6H5)COOH
Numero CAS:
1170-76-9
Peso molecolare:
356.37
Beilstein:
2182728
Numero CE:
214-626-9
Numero MDL:
MFCD00037264
Codice UNSPSC:
12352200
ID PubChem:
57653752
NACRES:
NA.22

Saggio

≥99.0%

Forma fisica

powder

Attività ottica

[α]20/D +40±1°, c = 2.5% in ethanol

Impiego in reazioni chimiche

reaction type: solution phase peptide synthesis

Punto di fusione

125-132 °C

applicazioni

peptide synthesis

Stringa SMILE

OC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)OCc2ccccc2

InChI

1S/C19H20N2O5/c22-17(12-20-19(25)26-13-15-9-5-2-6-10-15)21-16(18(23)24)11-14-7-3-1-4-8-14/h1-10,16H,11-13H2,(H,20,25)(H,21,22)(H,23,24)/t16-/m0/s1
FLGYJBNDDWLTQR-INIZCTEOSA-N

Altre note

Z-protected dipeptide employed in the Anteunis′ test to determine racemization in peptide coupling

Codice della classe di stoccaggio

13 - Non Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)

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J L Roe et al.
Experimental cell research, 181(2), 542-550 (1989-04-01)
Metalloendoproteases have been implicated in a variety of fusion processes including plasma membrane fusion and exocytosis. As a prerequisite to skeleton formation in the sea urchin embryo, primary mesenchyme cells undergo fusion via filopodia to form syncytia. The spicule is
T J Wheeler
Biochimica et biophysica acta, 979(3), 331-340 (1989-03-13)
Three compounds which inhibit glucose transport in rat adipocytes have been proposed to act directly on the glucose transporter protein. We tested these proposals by examining the effects of the compounds on the stereospecific glucose uptake catalyzed by adipocyte membrane
M Roth et al.
Clinica chimica acta; international journal of clinical chemistry, 135(1), 65-71 (1983-11-30)
A method has been designed for the assay of pancreatic carboxypeptidase A in blood serum. It uses Z-Gly-Phe as the substrate and fluorimetric determination of the released phenylalanine in an amino acid analyser, which yields a measure of free carboxypeptidase
P Vander Elst et al.
International journal of peptide and protein research, 29(3), 318-330 (1987-03-01)
The active sequence Phe7-D-Trp8-Lys9-Thr10 of somatostatin has been cyclized through o-(aminomethyl)phenylacetic acid, a spacer molecule, designed to mimic a Gly-Gly dipeptide containing a cis-constrained peptide bond. The resulting analogue shows no GH-inhibition. A 2D n.m.r. study reveals conformations different from
C D McCallum et al.
Biochemistry, 34(6), 1815-1824 (1995-02-14)
Many membrane functions are modulated by the bulk biophysical properties of the membrane. Various compounds which alter membrane physical properties were investigated for their ability to modulate insulin receptor autophosphorylation and signaling. Compounds which raise the bilayer to hexagonal phase
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