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915092

Sigma-Aldrich

Poly(3-hydroxybutyric acid)

natural origin, average Mn ~500,000

Sinonimo/i:

P3HB, PHA, PHB, Polyhydroxybutyrate

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About This Item

Formula condensata:
(C4H6O2)nH2O
Numero CAS:
Codice UNSPSC:
12352106
NACRES:
NA.25

Livello qualitativo

Forma fisica

powder

PM

average Mn ~500,000

Colore

white to off-white

Temperatura di conservazione

2-8°C

Applicazioni

Poly(3-hydroxybutyric acid) (PHB) is a common polyhydroxyalkanoate (PHA), it has been widely used for food packaging, medical implants, biodegradable sutures and drug delivery systems due to its biocompatible and biodegradable properties. PHB has been investigated as drug delivery micro- and nano-carriers.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable


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Senthilkumar Pachiyappan et al.
IET nanobiotechnology, 13(4), 416-427 (2019-06-07)
In this study, polyhydroxybutyrate (PHB) nanoparticles were synthesised following nanoprecipitation method having different solvents and surfactant (Tween 80) concentrations. In this study, PHB nanoparticles were encapsulated with curcumin and subjected for sustained curcumin delivery. Both the curcumin loaded and unloaded
K Juni et al.
Critical reviews in therapeutic drug carrier systems, 3(3), 209-232 (1987-01-01)
Poly(hydroxy acids) so far have been examined for use in drug delivery in limited number, while the advantageous use of the polymers has been recognized due to their biodegradability and biocompatibility. Homo- and copolymers of lactic acid and glycolic acid
Sumeet Kapoor et al.
International journal of pharmaceutics, 511(2), 876-889 (2016-08-06)
Faster biodegradation, immunogenicity and lack of cell penetrative capabilities are hurdles in development of peptidyl drugs for cancer therapy. Polymeric carriers can be used to overcome these problems. The present study is focused on the use of polyhydroxybutyrate as a

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