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802409

7-Azido-4-Methylcoumarin

97%

Sinonimo/i:

4-Methyl-7-azidocoumarin, 7-Azido-4-methyl-2H-1-benzopyran-2-one

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Cambia visualizzazione
A voi/SKUDisponibilitàPrezzo
10 mg
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CHF 172.00

Informazioni su questo articolo

Formula empirica (notazione di Hill):
C10H7N3O2
Numero CAS:
Peso molecolare:
201.18
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352125
MDL number:
Assay:
97%
Form:
powder

CHF 172.00


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Quality Segment

assay

97%

form

powder

mp

117.8 °C

SMILES string

CC1=CC(=O)Oc2cc(ccc12)N=[N+]=[N-]

InChI

1S/C10H7N3O2/c1-6-4-10(14)15-9-5-7(12-13-11)2-3-8(6)9/h2-5H,1H3

InChI key

HEKDKVLIMUWRRZ-UHFFFAOYSA-N

Application

7-Azido-4-methylcoumarin (AzMC) is a fluorogenic probe useful for the detection of hydrogen sulfide (H2S). The aromatic azide moiety is selectively reduced in the presence of H2S, producing the fluorescent 7-amino-4-methylcoumarin (AMC) with a concomitant increase in fluorescence with λex = 365nm and λem = 450nm. The probe can be used both to monitor enzymatic production of H2S in vitro and also to visualize H2S in cells. The probe is highly sensitive and selective for H2S, providing a linear detection range in vitro between 200nm – 100μM H2S with 10μM probe, and reacting selectively with H2S in the presence of mM concentrations of cysteine, homocysteine, glutathionine and many other common biological analytes.

Caution: Use of this product with DTT, TCEP and/or biological thiols >25mM should be avoided for maximum efficiency.

AzMC is readily soluble in DMSO.

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Questo articolo
63759H2400393979
Umbelliferone 99%

Sigma-Aldrich

H24003

Umbelliferone

Umbelliferone suitable for fluorescence indicator, ≥98.0% (HPLC)

Sigma-Aldrich

93979

Umbelliferone

description

97%

description

≥97.0% (GC)

description

99%

description

suitable for fluorescence indicator, ≥98.0% (HPLC)

assay

97%

assay

≥97.0% (GC)

assay

99%

assay

≥98.0% (HPLC)

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

mp

117.8 °C

mp

-

mp

230 °C (dec.) (lit.)

mp

230 °C (dec.) (lit.), 230-234 °C

form

powder

form

solid

form

-

form

crystals


Classe di stoccaggio

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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Questions

  1. Which storage conditions do you recommend once the product is diluted (for short- and long-term storage)? 

    1 answer
    1. The solution stability of this product has not been determined. However, various sources report that solutions in DMSO(fresh) are stable for 1 month at -20°C and 6 months at -80°C when stored in aliquots and protected from light.

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