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779008

Sigma-Aldrich

α-Cyclodextrin

Produced by Wacker Chemie AG, Burghausen, Germany, Life Science, 98.0-101.0% cyclodextrin basis (HPLC)

Sinonimo/i:

Cavamax® W6 Pharma, alpha-Cyclodextrin, α-Schardinger dextrin, Cyclohexaamylose, Cyclomaltohexaose

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About This Item

Formula empirica (notazione di Hill):
C36H60O30
Numero CAS:
Peso molecolare:
972.84
Beilstein:
79627
Numero CE:
Numero MDL:
Codice UNSPSC:
12352005
ID PubChem:
NACRES:
NA.22

Grado

Produced by Wacker Chemie AG, Burghausen, Germany, Life Science

Saggio

98.0-101.0% cyclodextrin basis (HPLC)

Forma fisica

solid

Attività ottica

[α]/D 147.0 to 152.0° in H2O (USP)

Impurezze

≤0.20% reducing substances
≤0.25% β- and γ-cyclodextrin (each)
≤0.5% related substances
≤20 ppm residual solvents
≤5 ppm heavy metals (USP)

Residuo alla calcinazione

≤0.10% (USP)

Perdita

≤10.0% loss on drying

pH

5.0-8.0 (1% in solution)

Punto di fusione

>278 °C (dec.) (lit.)

Assorbimento

≤0.05 at 350-750 nm in solution at 1%
≤0.10 at 230-250 nm in solution at 1%

Compatibilità

positive for identity (Ph Eur)

Stringa SMILE

OC[C@H]1O[C@@H]2O[C@H]3[C@H](O)[C@@H](O)[C@H](O[C@@H]3CO)O[C@H]4[C@H](O)[C@@H](O)[C@H](O[C@@H]4CO)O[C@H]5[C@H](O)[C@@H](O)[C@H](O[C@@H]5CO)O[C@H]6[C@H](O)[C@@H](O)[C@H](O[C@@H]6CO)O[C@H]7[C@H](O)[C@@H](O)[C@H](O[C@@H]7CO)O[C@H]1[C@H](O)[C@H]2O

InChI

1S/C36H60O30/c37-1-7-25-13(43)19(49)31(55-7)62-26-8(2-38)57-33(21(51)15(26)45)64-28-10(4-40)59-35(23(53)17(28)47)66-30-12(6-42)60-36(24(54)18(30)48)65-29-11(5-41)58-34(22(52)16(29)46)63-27-9(3-39)56-32(61-25)20(50)14(27)44/h7-54H,1-6H2/t7-,8-,9-,10-,11-,12-,13-,14-,15-,16-,17-,18-,19-,20-,21-,22-,23-,24-,25-,26-,27-,28-,29-,30-,31-,32-,33-,34-,35-,36-/m1/s1
HFHDHCJBZVLPGP-RWMJIURBSA-N

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Applicazioni

α-Cyclodextrin can be used:
  • As a ligand in the complexation of nonionic surfactants and polyethylene glycols. α-cyclodextrin shows strong interaction with the surfactants that contains no benzene group.
  • To protect linoleic acid from oxidation.
  • In the synthesis of binuclear copper(II) complexes with cyclodextrins, which can be further used as a template for the preparation of copper nanoparticles incorporated on mesoporous silica.

Note legali

Cavasol is a registered trademark of Wacker Chemie AG

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 1

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable


Certificati d'analisi (COA)

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I clienti hanno visto anche

Cucurbituril and α-and β-Cyclodextrins as Ligands for the Complexation of Nonionic Surfactants and Polyethyleneglycols in Aqueous Solutions
Buschmann HJ, et al.
Journal of Inclusion Phenomena and Macrocyclic Chemistry, 37(1-4), 231-236 (2000)
One-step synthesis of copper nanoparticles containing mesoporous silica by nanocasting of binuclear copper (II) complexes with cyclodextrins.
Han B H and Antonietti M
Journal of Materials Chemistry, 13(7), 1793-1796 (2003)
Oxidation-stable linoleic acid by inclusion in α-cyclodextrin
Regiert M, et al.
Journal of Inclusion Phenomena and Macrocyclic Chemistry, 57(1-4), 471-474 (2007)
Jing Chang et al.
Nanoscale, 5(2), 813-820 (2012-12-14)
The fabrication and drug delivery of novel polypseudorotaxane micelles with small molecule coumarin derivative as hydrophobic segment were reported. 7-Carboxymethoxy coumarin was immobilized on the terminal hydroxyl groups of poly(ethylene glycol) (PEG). The modified PEG chains were threaded in α-cyclodextrins
Takayuki Anno et al.
International journal of pharmaceutics, 426(1-2), 239-247 (2012-02-07)
We previously reported that glucuronylglucosyl-β-cyclodextrin (GUG-β-CyD) conjugate with polyamidoamine starburst dendrimer (GUG-β-CDE conjugate) with the average degree of substitution (DS) of cyclodextrin (CyD) of 1.8 (GUG-β-CDE conjugate (DS 1.8)), showed remarkably higher gene transfer activity than α-CyD/dendrimer conjugate (α-CDE conjugate

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