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741884

Sigma-Aldrich

Poly(2-ethyl-2-oxazoline)

average Mn 20,000, PDI <1.4

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About This Item

Codice UNSPSC:
12162002
NACRES:
NA.23

Forma fisica

solid

PM

average Mn 20,000

Punto di fusione

>300 °C

Ind. polidispersione

<1.4

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Applicazioni

This Poly(2-ethyl-2-oxazoline) polymer is amorphous and water soluble with good temperature stability. Jordan and coworkers showed biocompatibility, no accumulation in tissue, and rapid clearance from the bloodstream1. End-group modified poly(2-ethyl-2-oxazoline)s have been conjugated to peptides2, and were shown as versatile alternatives to poly(ethylene glycol) (PEG) for both protein and small drug conjugation3.

Potential substitute for poly(vinyl alcohol) and poly(vinyl pyrrolidone). Sometimes it is used as an adhesion promoter in coatings. This is also sometimes used in heat sealing and remoistenable hot-melt adhesives. N-propionyl substituted linear polyethylenimine

Caratteristiche e vantaggi

Nonionic, water-soluble thermoplastic. Better heat stability than poly(vinyl alcohol). Good melt flow, shear stability and Newtonian characteristics. Water is a room temperature Theta solvent.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Certificati d'analisi (COA)

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Polyethylenimine, linear average Mn 5,000, PDI &#8804;1.3

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F. C. Gaertner, R. Luxenhofer, B. Blechert, R. Jordan, M. Essler
J. Controlled Release, 119, 291-300 (2007)
R. Luxenhofer, M. Lopez-Garcia, A. Frank, H. Kessler, R. Jordan
Polym. Mater. Sci. Eng., 95, 283-284 (2006)
A. Mero, G. Pasut, L. D. Via, M.W. M. Fijten, et al.
J. Controlled Release, 125, 87-95 (2008)
J H Jeong et al.
Journal of controlled release : official journal of the Controlled Release Society, 73(2-3), 391-399 (2001-08-23)
A series of linear poly(ethylenimine) (L-PEI) containing varying amounts of cationic charge density in its backbone was produced by controlled hydrolysis of poly(2-ethyl-2-oxazoline) (PEtOz) for using as a nonviral DNA transfection agent. The effects of cationic charge density and molecular
Issa Katime et al.
Applied spectroscopy, 57(7), 829-834 (2003-12-09)
This paper reports an FT-IR study of blends of poly(mono-n-alkyl itaconates) with poly(N,N-dimethylacrylamide) (PDMA) and poly(ethyloxazoline) (PEOX). Strong hydrogen bonding has been found, and both polybases have shown similar acceptor strengths. Derivative techniques show asymmetric profiles for the free carbonyl
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