729108
Poly(ethylene glycol) methyl ether thiol
average MN 800, chemical modification reagent thiol reactive, methoxy, thiol
Sinonimo/i:
Polyethylene glycol, Methoxy PEG thiol, Methoxypolyethylene glycol thiol, PEG thiol, mPEG thiol
About This Item
Prodotti consigliati
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product name
Poly(ethylene glycol) methyl ether thiol, average Mn 800
Forma fisica
solid
PM
average Mn 800
Impiego in reazioni chimiche
reagent type: chemical modification reagent
reactivity: thiol reactive
Impurezze
≤10% disulfide
Temp. transizione
Tm 32-37 °C
Mw/Mn
≤1.1
Estremità Ω
thiol
Estremità α
methoxy
Architettura del polimero
shape: linear
functionality: monofunctional
Temperatura di conservazione
2-8°C
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Applicazioni
It can be used as a precursor to synthesize PEG conjugated poly(β-amino ester) polyplexes for gene therapy.
Avvertenze
Warning
Indicazioni di pericolo
Consigli di prudenza
Classi di pericolo
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Organi bersaglio
Respiratory system
Codice della classe di stoccaggio
11 - Combustible Solids
Classe di pericolosità dell'acqua (WGK)
WGK 3
Certificati d'analisi (COA)
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Articoli
Progress in biotechnology fields such as tissue engineering and drug delivery is accompanied by an increasing demand for diverse functional biomaterials. One class of biomaterials that has been the subject of intense research interest is hydrogels, because they closely mimic the natural environment of cells, both chemically and physically and therefore can be used as support to grow cells. This article specifically discusses poly(ethylene glycol) (PEG) hydrogels, which are good for biological applications because they do not generally elicit an immune response. PEGs offer a readily available, easy to modify polymer for widespread use in hydrogel fabrication, including 2D and 3D scaffold for tissue culture. The degradable linkages also enable a variety of applications for release of therapeutic agents.
Designing biomaterial scaffolds mimicking complex living tissue structures is crucial for tissue engineering and regenerative medicine advancements.
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