512753

2-Chloro-6-methoxyphenylboronic acid

≥95%

• Sinonimo/i: 2-Chloro-6-methoxybenzeneboronic acid, 6-Chloro-2-methoxyphenylboronic acid
• Formula condensata: ClC₆H₃(OCH₃)B(OH)₂
• Numero CAS: 385370-80-9
• Peso molecolare: 186.40
• Numero MDL: MFCD04039878
• Codice UNSPSC: 12352103
• ID PubChem: 24873654
• NACRES: NA.22

Proprietà

• Saggio: ≥95%
• Punto di fusione: 162-165 °C (lit.)
• Gruppo funzionale: chloro
• Stringa SMILE: COc1cccc(Cl)c1B(O)O
• InChI: 1S/C7H8BClO3/c1-12-6-4-2-3-5(9)7(6)8(10)11/h2-4,10-11H,1H3; XNWCIDBPLDKKAG-UHFFFAOYSA-N

Descrizione

Applicazioni

2-Chloro-6-methoxyphenylboronic acid can be used as a reactant:

• In the palladium-catalyzed Suzuki-Miyaura coupling reaction.[1][2]
• To synthesize canthin-6-one alkaloids by reacting with 8-bromo-1,5-naphthyridin-2-one via Pd-catalyzed Suzuki coupling and Cu-catalyzed amidation reactions.[2]
• To prepare tryptamines via Suzuki coupling of vinylsulfonylmethyl resin-bound bromotryptamine.[3]

Reactant for:

• Suzuki coupling
• Preparation of inhibitors of cholesteryl ester transfer protein to raise HDLc levels
• Pd-catalyzed Suzuki-Miyaura coupling
• Solid-phase synthesis of 2,3,5-trisubstituted indoles

Altre note

Contains varying amounts of anhydride

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 13 - Non Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable
• Dispositivi di protezione individuale: Eyeshields, Gloves, type N95 (US)