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341517

Sigma-Aldrich

Tetrahydro-2-furoic acid

97%

Sinonimo/i:

Tetrahydrofuran-2-carboxylic acid

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About This Item

Formula empirica (notazione di Hill):
C5H8O3
Numero CAS:
16874-33-2
Peso molecolare:
116.12
Beilstein:
109671
Numero MDL:
MFCD00022473
Codice UNSPSC:
12352100
ID PubChem:
24860955
NACRES:
NA.22

Saggio

97%

Forma fisica

liquid

contiene

250 ppm BHT as inhibitor

Indice di rifrazione

n20/D 1.46 (lit.)

P. eboll.

128-129 °C/13 mmHg (lit.)
237-243 °C (lit.)

Densità

1.209 g/mL at 25 °C (lit.)

Stringa SMILE

OC(=O)C1CCCO1

InChI

1S/C5H8O3/c6-5(7)4-2-1-3-8-4/h4H,1-3H2,(H,6,7)
UJJLJRQIPMGXEZ-UHFFFAOYSA-N

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Descrizione generale

Tetrahydro-2-furoic acid inhibits the programmed cell death of Xanthomonas campestris strains. It is a specific inhibitor of proline dehydrogenase, a mitochondrial flavoenzyme that oxidizes proline.

Pittogrammi

Corrosion
GHS05

Avvertenze

Danger

Indicazioni di pericolo

H314

Classi di pericolo

Skin Corr. 1B

Codice della classe di stoccaggio

8A - Combustible corrosive hazardous materials

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

235.4 °F - closed cup

Punto d’infiammabilità (°C)

113 °C - closed cup

Dispositivi di protezione individuale

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

Certificati d'analisi (COA)

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Surbhi Wadhawan et al.
PloS one, 9(5), e96423-e96423 (2014-05-03)
Xanthomonas campestris strains have been reported to undergo programmed cell death (PCD) in a protein rich medium. Protein hydrolysates used in media such as nutrient broth comprise of casein digest with abundance of proline and glutamate. In the current study
Navasona Krishnan et al.
Free radical biology & medicine, 44(4), 671-681 (2007-11-27)
The potential of proline to suppress reactive oxygen species (ROS) and apoptosis in mammalian cells was tested by manipulating intracellular proline levels exogenously and endogenously by overexpression of proline metabolic enzymes. Proline was observed to protect cells against H(2)O(2), tert-butyl
S Bando et al.
Acta crystallographica. Section C, Crystal structure communications, 46 ( Pt 1), 106-108 (1990-01-15)
C5H10O4, Mr = 134.31, monoclinic, P2(1), a = 11.670 (2), b = 6.177 (3), c = 10.704 (2) A, beta = 115.11 (2) degrees, V = 698.7 (4) A3, Z = 4, Dm = 1.26, Dx = 1.28 g cm-3
Chengwen Feng et al.
Animals : an open access journal from MDPI, 10(9) (2020-09-05)
Proline was reported to improve sperm quality in rams, stallions, cynomolgus monkeys, donkeys, and canines during cryopreservation. However, the underlying mechanism remains unclear. The aim of this study was to investigate the effect of proline on boar semen during liquid
Tatsuki Sato et al.
BioMed research international, 2020, 7245782-7245782 (2020-12-05)
Candida albicans undergoes a yeast-to-hyphal transition that has been recognized as a virulence property as well as a turning point leading to biofilm formation associated with candidiasis. It is known that yeast-to-hyphal transition is induced under complex environmental conditions including
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