230715

n-Butillitio

11.0 M in hexanes

• Sinonimo/i: n-BuLi, Butillitio, Litio-1-butanide
• Formula condensata: CH₃(CH₂)₃Li
• Numero CAS: 109-72-8
• Peso molecolare: 64.06
• Beilstein: 1209227
• Numero MDL: MFCD00009414
• Codice UNSPSC: 12352103
• ID PubChem: 24853833
• NACRES: NA.22

Proprietà

• Forma fisica: liquid
• Livello qualitativo: 100
• Concentrazione: 11.0 M in hexanes
• Densità: 0.761 g/mL at 25 °C
• Temperatura di conservazione: 2-8°C
• Stringa SMILE: [Li]CCCC
• InChI: 1S/C4H9.Li/c1-3-4-2;/h1,3-4H2,2H3;; MZRVEZGGRBJDDB-UHFFFAOYSA-N

Descrizione

Descrizione generale

n-Butyllithium (n-BuLi) is an organolithium reagent commonly used as a strong base to form corresponding lithium salts by the deprotonation of nitrogen, oxygen, phosphorus, and carbon acids. Heterocyclic compounds, such as furans, thiophenes, oxazoles, pyrroles, etc, can be lithiated α to the ring heteroatom using n?BuLi. These lithiated salts reacting in situ with alkyl halides to obtain useful organic compounds by the formation of the C-C bond.

Applicazioni

n-BuLi can be used as a reagent for lithium-halogen exchange reactions. Synthesis of various other useful reagents such as lithium diisopropylamide (LDA) and diphenylphosphine is prepared by in situ reaction with n-BuLi . In the polymerization of dienes, it can be employed as an initiator.

Confezionamento

The 25 mL Sure/Seal^™ bottle is recommended as a single-use bottle. Repeated punctures will likely result in decreased performance of product.

Note legali

Sure/Seal is a trademark of Sigma-Aldrich Co. LLC

Informazioni sulla sicurezza

• Pittogrammi: GHS02,GHS08,GHS05,GHS07,GHS09
• Avvertenze: Danger
• Indicazioni di pericolo: H225,H250,H260,H304,H314,H336,H361f,H372,H411
• Consigli di prudenza: P210 - P231 + P232 - P280 - P301 + P330 + P331 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 - P370 + P378
• Classi di pericolo: Aquatic Chronic 2 - Asp. Tox. 1 - Eye Dam. 1 - Flam. Liq. 2 - Pyr. Liq. 1 - Repr. 2 - Skin Corr. 1B - STOT RE 1 Inhalation - STOT SE 3 - Water-react 1
• Organi bersaglio: Central nervous system, Nervous system
• Rischi supp: EUH014
• Codice della classe di stoccaggio: 4.2 - Pyrophoric and self-heating hazardous materials
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): -7.6 °F - closed cup
• Punto d’infiammabilità (°C): -22 °C - closed cup
• Dispositivi di protezione individuale: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter