TEK
TEK tyrosine kinase, endothelial
Sinonimi:
CD202B, TIE-2, TIE2, VMCM, VMCM1
Specie:
Human TEK (7010), Mouse Tek (21687), Rat Tek (89804), chicken TEK (427368), Zebrafish tek (30747), dog TEK (403714), domestic cat TEK (101091977), cow TEK (280939), domestic guinea pig Tek (100713324), naked mole-rat Tek (101710501)
ID UniProtKB:
ID gene:
- Human(7010) Summary: The TEK receptor tyrosine kinase is expressed almost exclusively in endothelial cells in mice, rats, and humans. This receptor possesses a unique extracellular domain containing 2 immunoglobulin-like loops separated by 3 epidermal growth factor-like repeats that are connected to 3 fibronectin type III-like repeats. The ligand for the receptor is angiopoietin-1. Defects in TEK are associated with inherited venous malformations; the TEK signaling pathway appears to be critical for endothelial cell-smooth muscle cell communication in venous morphogenesis. TEK is closely related to the TIE receptor tyrosine kinase. [provided by RefSeq, Jul 2008]
- Mouse(21687) endothelial-specific receptor tyrosine kinase
- Rat(89804) TEK tyrosine kinase, endothelial
- chicken(427368) TEK tyrosine kinase, endothelial
- Zebrafish(30747) TEK tyrosine kinase, endothelial
- dog(403714) TEK tyrosine kinase, endothelial
- domestic cat(101091977) TEK tyrosine kinase, endothelial
- cow(280939) TEK tyrosine kinase, endothelial
- domestic guinea pig(100713324) TEK tyrosine kinase, endothelial
- naked mole-rat(101710501) TEK tyrosine kinase, endothelial
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ELISA
Antibodies
N° Catalogo
Descrizione
Reattività con
Applicazione
Anticorpo anti-Tie2/TEK, clone Ab33, clone Ab33, Upstate®, from mouse,
Reattività con
human, mouse, pig, rat
Applicazione
immunohistochemistry
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Anti-phospho-TIE2 (pTyr1108) antibody produced in rabbit, affinity isolated antibody,
Reattività con
human, mouse, rat
Applicazione
ELISA
immunofluorescence
western blot
immunofluorescence
western blot
Anti-phospho TIE2/TEK Antibody (Tyr992), 0.25 mg/mL, from rabbit,
Reattività con
bovine, human, mouse, rat, zebrafish
Applicazione
immunoprecipitation (IP)
inhibition assay
western blot
inhibition assay
western blot
ANTI-TEK antibody produced in mouse, clone 4G9, purified immunoglobulin, buffered aqueous solution,
Reattività con
human
Applicazione
ELISA
western blot
western blot
Anti-Tie-2 Antibody, clone 1C5 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reattività con
bovine, canine, human, monkey, mouse, rat
Applicazione
affinity binding assay
immunocytochemistry
western blot
immunocytochemistry
western blot
Small Molecule - Inhibitor
N° Catalogo
Descrizione
Specie
7-Cyclopentyl-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3‑d]pyrimidin-4-ylamine, ≥98% (HPLC),
Specie
human
Proteins
N° Catalogo
Descrizione
Specie
Tie2 Protein, active, 10 µg, Active, N-terminal His6-tagged recombinant human Tie2 residues 771-end, for use in Kinase Assays.,
Specie
human
TIE2 (771-end), active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Specie
human