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Merck

SLC6A2

solute carrier family 6 (neurotransmitter transporter), member 2

Sinonimi:
NAT1, NET, NET1, SLC6A5
Specie:
ID UniProtKB:
ID gene:
  • Human(6530) Summary: This gene encodes a member of the sodium:neurotransmitter symporter family. This member is a multi-pass membrane protein, which is responsible for reuptake of norepinephrine into presynaptic nerve terminals and is a regulator of norepinephrine homeostasis. Mutations in this gene cause orthostatic intolerance, a syndrome characterized by lightheadedness, fatigue, altered mentation and syncope. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene.[provided by RefSeq, Feb 2010]
  • Mouse(20538) solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2
  • Rat(83511) solute carrier family 6 (neurotransmitter transporter), member 2
  • domestic guinea pig(100723578) solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2
  • naked mole-rat(101716834) solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2
  • sheep(101116078) solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2
  • sheep(443100) solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2
  • Domestic Rabbit(100328959) solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2
  • dog(487272) solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2
  • domestic cat(101099605) solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2
  • domestic cat(493768) solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2
  • Horse(100061346) solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2
  • cow(282363) solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2
  • chicken(395458) solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2

Custom & Knockdown Gene Products

Small Molecule - Antagonist

Numero di prodotto
Descrizione
Specie
Nefazodone hydrochloride, ≥98% (HPLC), solid,
Specie
human
Nefazodone hydrochloride, United States Pharmacopeia (USP) Reference Standard,
Specie
human
Amoxapine, 1.0 mg/mL in methanol, certified reference material, Cerilliant®,
Specie
human
Amoxapine, United States Pharmacopeia (USP) Reference Standard,
Specie
human
Amoxapine, Pharmaceutical Secondary Standard; Certified Reference Material,
Specie
human

Antibodies

Numero di prodotto
Descrizione
Reattività con
Applicazione
Anti-SLC6A2 antibody produced in rabbit, affinity isolated antibody,
Reattività con
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Applicazione
western blot
Anti-SLC6A2, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reattività con
human
Applicazione
immunohistochemistry
Anti-SLC6A2 antibody produced in rabbit, affinity isolated antibody,
Reattività con
bovine, canine, guinea pig, horse, human, mouse, rabbit, rat
Applicazione
western blot
Anti-Norepinephrine Transporter Antibody, ascites fluid, Chemicon®,
Reattività con
human, monkey
Applicazione
immunohistochemistry
Anti-Norepinephrine Transporter Antibody, Chemicon®, from rabbit,
Reattività con
mouse, rat
Applicazione
ELISA
western blot

Small Molecule - Inhibitor

Numero di prodotto
Descrizione
Specie
Atomoxetine Hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material,
Specie
human
Desipramine hydrochloride solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®,
Specie
human
Atomoxetine hydrochloride, United States Pharmacopeia (USP) Reference Standard,
Specie
human
Maprotiline hydrochloride, >99% (HPLC), powder,
Specie
human
Desipramine hydrochloride, United States Pharmacopeia (USP) Reference Standard,
Specie
human

esiRNA

Numero di prodotto
Descrizione
Specie
MISSION® esiRNA, targeting human SLC6A2,
Specie
human

Small Molecule - Substrate

Numero di prodotto
Descrizione
Specie
Guanethidine monosulfate, United States Pharmacopeia (USP) Reference Standard,
Specie
human
Guanethidine monosulfate, British Pharmacopoeia (BP) Reference Standard,
Specie
human
Bretylium tosylate, United States Pharmacopeia (USP) Reference Standard,
Specie
human