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Merck

PRKCZ

protein kinase C, zeta

Sinonimi:
PKC-ZETA, PKC2
Specie:
ID UniProtKB:
ID gene:
  • Human(5590) Summary: Protein kinase C (PKC) zeta is a member of the PKC family of serine/threonine kinases which are involved in a variety of cellular processes such as proliferation, differentiation and secretion. Unlike the classical PKC isoenzymes which are calcium-dependent, PKC zeta exhibits a kinase activity which is independent of calcium and diacylglycerol but not of phosphatidylserine. Furthermore, it is insensitive to typical PKC inhibitors and cannot be activated by phorbol ester. Unlike the classical PKC isoenzymes, it has only a single zinc finger module. These structural and biochemical properties indicate that the zeta subspecies is related to, but distinct from other isoenzymes of PKC. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
  • Mouse(18762) protein kinase C, zeta
  • Rat(25522) protein kinase C, zeta
  • dog(479577) protein kinase C, zeta
  • chicken(419399) protein kinase C, zeta
  • domestic cat(101087851) protein kinase C, zeta
  • Domestic Rabbit(100009538) protein kinase C, zeta
  • sheep(101122295) protein kinase C, zeta
  • naked mole-rat(101699303) protein kinase C, zeta
  • domestic guinea pig(100734946) protein kinase C, zeta
  • cow(286877) protein kinase C, zeta
  • Zebrafish(555737) protein kinase C, zeta

Custom & Knockdown Gene Products

Antibodies

Numero di prodotto
Descrizione
Reattività con
Applicazione
Anti-PKC ζ antibody produced in rabbit, affinity isolated antibody,
Reattività con
human, mouse, rat
Applicazione
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-PRKCZ antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human, mouse
Applicazione
immunofluorescence
immunohistochemistry

western blot
Anti-PKC ζ Antibody, clone 1F20 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reattività con
human
Applicazione
ELISA
affinity binding assay

western blot
Anti-Phospho-PKC zeta-T560 antibody produced in rabbit, ,
Reattività con
human
Applicazione
western blot
Anti-phospho-PKC ζ (pThr410) antibody produced in rabbit, affinity isolated antibody,
Reattività con
human, mouse, rat
Applicazione
ELISA
immunofluorescence

immunohistochemistry

western blot

Small Molecule - Inhibitor

Numero di prodotto
Descrizione
Specie
UCN-01, ≥97% (HPLC), powder,
Specie
human
GSK690693, ≥98% (HPLC),
Specie
human

Proteins

Numero di prodotto
Descrizione
Specie
Protein Kinase Cζ isozyme human, ≥75% (SDS-PAGE), recombinant, expressed in baculovirus infected insect cells, buffered aqueous solution,
Specie
human

esiRNA

Numero di prodotto
Descrizione
Specie
MISSION® esiRNA, targeting human PRKCZ,
Specie
human