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Merck

PRKCE

protein kinase C, epsilon

Sinonimi:
PKCE, nPKC-epsilon
Specie:
ID UniProtKB:
ID gene:
  • Human(5581) Summary: Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This kinase has been shown to be involved in many different cellular functions, such as neuron channel activation, apoptosis, cardioprotection from ischemia, heat shock response, as well as insulin exocytosis. Knockout studies in mice suggest that this kinase is important for lipopolysaccharide (LPS)-mediated signaling in activated macrophages and may also play a role in controlling anxiety-like behavior. [provided by RefSeq, Jul 2008]
  • Mouse(18754) protein kinase C, epsilon
  • Rat(29340) protein kinase C, epsilon
  • chicken(421409) protein kinase C, epsilon
  • domestic cat(101100958) protein kinase C, epsilon
  • dog(609934) protein kinase C, epsilon
  • cow(507041) protein kinase C, epsilon
  • Horse(100053394) protein kinase C, epsilon
  • Domestic Rabbit(100009103) protein kinase C, epsilon
  • sheep(101110314) protein kinase C, epsilon
  • naked mole-rat(101700837) protein kinase C, epsilon
  • domestic guinea pig(100721814) protein kinase C, epsilon

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Small Molecule - Agonist

N° Catalogo
Descrizione
Specie
Acido oleico, ≥99% (GC),
Specie
human

Antibodies

N° Catalogo
Descrizione
Reattività con
Applicazione
Anticorpo anti-PKCε, Upstate®, from rabbit,
Reattività con
human, mouse, rat
Applicazione
immunohistochemistry
immunoprecipitation (IP)

western blot
Anti-phospho-PKCepsilon Antibody (Ser729), from rabbit, purified by affinity chromatography,
Reattività con
human, mouse, rat
Applicazione
western blot
Anti-PRKCE antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunohistochemistry
western blot
Anti-PRKCE antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reattività con
human
Applicazione
immunofluorescence
Anti-PKC ε antibody produced in rabbit, affinity isolated antibody,
Reattività con
human, mouse, rat
Applicazione
ELISA
western blot

Small Molecule - Inhibitor

N° Catalogo
Descrizione
Specie
H-7 dihydrochloride, ≥98% (HPLC),
Specie
human
Tamoxifen citrate salt, ≥99%,
Specie
human
Acido oleico, ≥99% (GC),
Specie
human
UCN-01, ≥97% (HPLC), powder,
Specie
human
GSK690693, ≥98% (HPLC),
Specie
human

Proteins

N° Catalogo
Descrizione
Specie
PKCε Protein, active, 10 µg, Active, N-terminal His6-tagged, recombinant PKCε, amino acids 2-end. For use in Kinase Assays.,
Specie
human
PKC ε , active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Specie
human

esiRNA

N° Catalogo
Descrizione
Specie
MISSION® esiRNA, targeting mouse Prkce,
Specie
mouse
MISSION® esiRNA, targeting human PRKCE,
Specie
human