Passa al contenuto
Merck

PDGFB

platelet-derived growth factor beta polypeptide

Sinonimi:
PDGF-2, PDGF2, SIS, SSV, c-sis
Specie:
ID UniProtKB:
ID gene:
  • Human(5155) Summary: The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a motif of eight cysteines. This gene product can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. Mutations in this gene are associated with meningioma. Reciprocal translocations between chromosomes 22 and 17, at sites where this gene and that for collagen type 1, alpha 1 are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans resulting from unregulated expression of growth factor. Two alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Feb 2013]
  • Mouse(18591) platelet derived growth factor, B polypeptide
  • Rat(24628) platelet-derived growth factor beta polypeptide
  • naked mole-rat(101698830) platelet-derived growth factor beta polypeptide
  • dog(442986) platelet-derived growth factor beta polypeptide
  • sheep(443545) platelet-derived growth factor beta polypeptide
  • domestic guinea pig(100731469) platelet-derived growth factor beta polypeptide
  • cow(540106) platelet-derived growth factor beta polypeptide
  • chicken(374128) platelet-derived growth factor beta polypeptide
  • Zebrafish(565324) platelet derived growth factor, B polypeptide

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

ELISA

N° Catalogo
Descrizione
Specie
Human PDGF-BB ELISA Kit, for serum, plasma, cell culture supernatant and urine,
Specie
human
Human PDGF-BB ELISA Kit, for cell and tissue lysates,
Specie
human
Porcine PDGFB / Platelet-derived Growth Factor Subunit B ELISA Kit, ,
Specie
Canine PDGFB / Platelet-derived Growth Factor Subunit B ELISA Kit, ,
Specie
dog
Rhesus Macaque PDGF-BB ELISA, for serum, plasma and cell culture supernatants,
Specie

Antibodies

N° Catalogo
Descrizione
Reattività con
Applicazione
Anti-PDGFB antibody produced in rabbit, affinity isolated antibody,
Reattività con
human, mouse, rat
Applicazione
ELISA
western blot
Anti-Platelet-Derived Growth Factor-BB antibody produced in goat, affinity isolated antibody, lyophilized powder,
Reattività con
human
Applicazione
neutralization
western blot
Anti-PDGF-BB Antibody, from rabbit, purified by affinity chromatography,
Reattività con
human
Applicazione
ELISA
neutralization

western blot
Anti-PDGFB antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Reattività con
human
Applicazione
western blot
Anti-PDGF-BB Antibody, clone 6A9.9.11, ,
Reattività con
human
Applicazione
immunohistochemistry
western blot

Proteins

N° Catalogo
Descrizione
Specie
Platelet-Derived Growth Factor-BB human, PDGF-BB, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture,
Specie
human
Platelet-Derived Growth Factor from porcine platelets, PDGF, lyophilized powder, suitable for cell culture,
Specie
PDGF-BB, ricombinante umana, The Platelet Derived Growth Factor (PDGF) is a potent mitogen for a wide range of cell types including fibroblasts, smooth muscle & connective tissue.,
Specie
human
PDGF-BB human, Animal-component free, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture,
Specie
human
Platelet-Derived Growth Factor-BB human, PDGF-BB, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture,
Specie
human

esiRNA

N° Catalogo
Descrizione
Specie
MISSION® esiRNA, targeting human PDGFB,
Specie
human