OPTN
optineurin
Sinonimi:
ALS12, FIP2, GLC1E, HIP7, HYPL, NRP, TFIIIA-INTP
Specie:
Human OPTN (10133), Mouse Optn (71648), Rat Optn (246294), domestic guinea pig Optn (100722896), naked mole-rat Optn (101725616), domestic cat OPTN (101087414), cow OPTN (534150), sheep OPTN (101106703), chicken OPTN (374079), dog OPTN (478003)
ID UniProtKB:
ID gene:
- Human(10133) Summary: This gene encodes the coiled-coil containing protein optineurin. Optineurin may play a role in normal-tension glaucoma and adult-onset primary open angle glaucoma. Optineurin interacts with adenovirus E3-14.7K protein and may utilize tumor necrosis factor-alpha or Fas-ligand pathways to mediate apoptosis, inflammation or vasoconstriction. Optineurin may also function in cellular morphogenesis and membrane trafficking, vesicle trafficking, and transcription activation through its interactions with the RAB8, huntingtin, and transcription factor IIIA proteins. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008]
- Mouse(71648) optineurin
- Rat(246294) optineurin
- domestic guinea pig(100722896) optineurin
- naked mole-rat(101725616) optineurin
- domestic cat(101087414) optineurin
- cow(534150) optineurin
- sheep(101106703) optineurin
- chicken(374079) optineurin
- dog(478003) optineurin
- Zebrafish(336159) optineurin
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Antibodies
N° Catalogo
Descrizione
Reattività con
Applicazione
Anti-OPTN antibody produced in rabbit, Ab1, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-OPTN antibody produced in rabbit, Ab2, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-OPTN antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Reattività con
human
Applicazione
immunofluorescence
western blot
western blot
Anti-OPTN antibody produced in rabbit, affinity isolated antibody,
Reattività con
dog, guinea pig, horse, human, mouse, rabbit, rat
Applicazione
western blot
Anti-OPTN (ab2) antibody produced in rabbit, affinity isolated antibody,
Reattività con
guinea pig, human
Applicazione
western blot
esiRNA
N° Catalogo
Descrizione
Specie