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Merck

NDUFA1

NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa

Sinonimi:
CI-MWFE, MWFE, ZNF183
Specie:
ID UniProtKB:
ID gene:
  • Human(4694) Summary: The human NDUFA1 gene codes for an essential component of complex I of the respiratory chain, which transfers electrons from NADH to ubiquinone. It has been noted that the N-terminal hydrophobic domain has the potential to be folded into an alpha-helix spanning the inner mitochondrial membrane with a C-terminal hydrophilic domain interacting with globular subunits of complex I. The highly conserved two-domain structure suggests that this feature is critical for the protein function and might act as an anchor for the NADH:ubiquinone oxidoreductase complex at the inner mitochondrial membrane. However, the NDUFA1 peptide is one of about 31 components of the 'hydrophobic protein' (HP) fraction of complex I which is involved in proton translocation. Thus the NDUFA1 peptide may also participate in that function. [provided by RefSeq, Jul 2008]
  • Mouse(54405) NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1
  • Rat(363441) NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1
  • dog(481033) NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa
  • domestic cat(101085609) NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa
  • chicken(772150) NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa
  • naked mole-rat(101713738) NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa
  • Zebrafish(415243) NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1
  • cow(327673) NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa
  • sheep(100216464) NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa

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Antibodies

N° Catalogo
Descrizione
Reattività con
Applicazione
Anti-NDUFA1 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Reattività con
human
Applicazione
western blot
Anti-NDUFA1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reattività con
human
Applicazione
immunofluorescence
Monoclonal Anti-NDUFA1 antibody produced in mouse, clone 3B9-1A1, purified immunoglobulin, buffered aqueous solution,
Reattività con
human
Applicazione
ELISA
western blot
Anti-NDUFA1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunohistochemistry
Monoclonal Anti-NDUFA1 antibody produced in mouse, clone 2A4, purified immunoglobulin, buffered aqueous solution,
Reattività con
human
Applicazione
ELISA

Small Molecule - Inhibitor

N° Catalogo
Descrizione
Specie
Metformin hydrochloride, United States Pharmacopeia (USP) Reference Standard,
Specie
human
1,1-Dimethylbiguanide hydrochloride, 97%,
Specie
human
Metformin hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material,
Specie
human
Metformin hydrochloride solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®,
Specie
human
Metformin hydrochloride, European Pharmacopoeia (EP) Reference Standard,
Specie
human

esiRNA

N° Catalogo
Descrizione
Specie
MISSION® esiRNA, targeting human NDUFA1,
Specie
human