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Merck

MTNR1A

melatonin receptor 1A

Sinonimi:
MEL-1A-R, MT1
Specie:
ID UniProtKB:
ID gene:
  • Human(4543) Summary: This gene encodes one of two high affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal gland. This receptor is a G-protein coupled, 7-transmembrane receptor that is responsible for melatonin effects on mammalian circadian rhythm and reproductive alterations affected by day length. The receptor is an integral membrane protein that is readily detectable and localized to two specific regions of the brain. The hypothalamic suprachiasmatic nucleus appears to be involved in circadian rhythm while the hypophysial pars tuberalis may be responsible for the reproductive effects of melatonin. [provided by RefSeq, Jul 2008]
  • Mouse(17773) melatonin receptor 1A
  • Rat(114211) melatonin receptor 1A
  • dog(482904) melatonin receptor 1A
  • sheep(443022) melatonin receptor 1A
  • chicken(396319) melatonin receptor 1A
  • naked mole-rat(101719975) melatonin receptor 1A
  • domestic guinea pig(100720785) melatonin receptor 1A
  • cow(539948) melatonin receptor 1A
  • domestic cat(101098297) melatonin receptor 1A

Custom & Knockdown Gene Products

Small Molecule - Agonist

Numero di prodotto
Descrizione
Specie
6-Hydroxymelatonin, ,
Specie
human
Ramelteon, ,
Specie
human
Agomelatine, ≥98% (HPLC),
Specie
human

Small Molecule - Antagonist

Numero di prodotto
Descrizione
Specie
Luzindole, ≥90%,
Specie
human
Agomelatine, ≥98% (HPLC),
Specie
human
Melatonin, powder, ≥98% (TLC),
Specie
human

Antibodies

Numero di prodotto
Descrizione
Reattività con
Applicazione
Anti-MTNR1A antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Reattività con
human
Applicazione
ELISA
western blot

Small Molecule - Ligand

Numero di prodotto
Descrizione
Specie
Melatonin, powder, ≥98% (TLC),
Specie
human

Small Molecule - Precursor

Numero di prodotto
Descrizione
Specie
N-Acetyl-5-hydroxytryptamine, ≥99% (HPLC), powder,
Specie
human

esiRNA

Numero di prodotto
Descrizione
Specie
MISSION® esiRNA, targeting human MTNR1A,
Specie
human