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Merck

MMP8

matrix metallopeptidase 8 (neutrophil collagenase)

Sinonimi:
CLG1, HNC, MMP-8, PMNL-CL
Specie:
ID UniProtKB:
ID gene:
  • Human(4317) Summary: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the enzyme encoded by this gene is stored in secondary granules within neutrophils and is activated by autolytic cleavage. Its function is degradation of type I, II and III collagens. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. [provided by RefSeq, Jul 2008]
  • Mouse(17394) matrix metallopeptidase 8
  • Rat(63849) matrix metallopeptidase 8
  • domestic guinea pig(100724670) matrix metallopeptidase 8 (neutrophil collagenase)
  • naked mole-rat(101716969) matrix metallopeptidase 8 (neutrophil collagenase)
  • sheep(101120601) matrix metallopeptidase 8 (neutrophil collagenase)
  • domestic cat(101080995) matrix metallopeptidase 8 (neutrophil collagenase)
  • Horse(100069005) matrix metallopeptidase 8 (neutrophil collagenase)
  • cow(100336575) matrix metallopeptidase 8 (neutrophil collagenase)
  • dog(489429) matrix metallopeptidase 8 (neutrophil collagenase)

Custom & Knockdown Gene Products

ELISA

Numero di prodotto
Descrizione
Specie
Human MMP-8 ELISA Kit, for serum, plasma, conditioned medium, urine,
Specie
human
Rat MMP-8 ELISA Kit, for serum, plasma, cell culture supernatant,
Specie
mouse

Antibodies

Numero di prodotto
Descrizione
Reattività con
Applicazione
Anti-MMP8 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution, Ab2,
Reattività con
human
Applicazione
immunohistochemistry
Anti-MMP8 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution, Ab1,
Reattività con
human
Applicazione
immunohistochemistry
Anti-Mmp8 Antibody Produced In Rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunofluorescence

Small Molecule - Inhibitor

Numero di prodotto
Descrizione
Specie
Doxycycline monohydrate, ,
Specie
human
Doxycycline Monohydrate, United States Pharmacopeia (USP) Reference Standard,
Specie
human
α-Sexithiophene, ,
Specie
human, rat
Marimastat, ≥98% (HPLC),
Specie
human, rat, mouse
CP-101537, ≥98% (HPLC),
Specie
human, rat, mouse

esiRNA

Numero di prodotto
Descrizione
Specie
MISSION® esiRNA, targeting human MMP8,
Specie
human