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Merck

MMP2

matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)

Sinonimi:
CLG4, CLG4A, MMP-II, MONA, TBE-1
Specie:
ID UniProtKB:
ID gene:
  • Human(4313) Summary: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades type IV collagen, the major structural component of basement membranes. The enzyme plays a role in endometrial menstrual breakdown, regulation of vascularization and the inflammatory response. Mutations in this gene have been associated with Winchester syndrome and Nodulosis-Arthropathy-Osteolysis (NAO) syndrome. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(17390) matrix metallopeptidase 2
  • Rat(81686) matrix metallopeptidase 2
  • naked mole-rat(101696977) matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
  • cow(282872) matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
  • sheep(443115) matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
  • chicken(386583) matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
  • domestic guinea pig(100719361) matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
  • dog(403733) matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
  • Zebrafish(337179) matrix metalloproteinase 2
  • Horse(100033948) matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
  • Domestic Rabbit(100009000) matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
  • domestic cat(101098838) matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
  • fruit fly(35997) Matrix metalloproteinase 2

Custom & Knockdown Gene Products

ELISA

Numero di prodotto
Descrizione
Specie
Human MMP-2 ELISA Kit, for serum, plasma, cell culture supernatant,
Specie
human
Mouse MMP-2 ELISA Kit, for serum, plasma and cell culture supernatant,
Specie
mouse
Rat MMP-2 ELISA, for serum, plasma and cell culture supernatants,
Specie
rat

Antibodies

Numero di prodotto
Descrizione
Reattività con
Applicazione
Anti-MMP-2 Antibody, a.a. 468-483 hMMP2, clone 42-5D11, clone 42-5D11, Chemicon®, from mouse,
Reattività con
bovine, horse, human, mouse, pig, rabbit, rat
Applicazione
ELISA
immunohistochemistry

western blot
Anti-MMP-2 (Ab-3) Mouse mAb (42-5D11), liquid, clone 42-5D11, Calbiochem®,
Reattività con
bovine, human, mouse, rat
Applicazione
Anti-MMP-2 antibody produced in rabbit, affinity isolated antibody,
Reattività con
human, mouse, rat
Applicazione
ELISA
western blot
Anti-MMP2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunohistochemistry
western blot
Anti-MMP-2 Antibody, pro and active form, clone A-Gel VC2, clone A-Gel VC2, Chemicon®, from mouse,
Reattività con
human
Applicazione
ELISA
immunohistochemistry

Small Molecule - Inhibitor

Numero di prodotto
Descrizione
Specie
Marimastat, ≥98% (HPLC),
Specie
human, rat, mouse
CP-101537, ≥98% (HPLC),
Specie
human, rat, mouse
PD166793 hydrate, ≥98% (HPLC),
Specie
human, rat, mouse

Proteins

Numero di prodotto
Descrizione
Specie
MMP-2 human, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture,
Specie
human
Matrix Metalloproteinase-2, >90% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder,
Specie
human
Matrix Metalloproteinase-2, recombinant, expressed in NSO cells, >95% (SDS-PAGE), buffered aqueous glycerol solution,
Specie
mouse, rat

esiRNA

Numero di prodotto
Descrizione
Specie
MISSION® esiRNA, targeting mouse Mmp2,
Specie
mouse
MISSION® esiRNA, targeting human MMP2,
Specie
human