MBP
myelin basic protein
Sinonimi:
Specie:
Human MBP (4155), Mouse Mbp (17196), Rat Mbp (24547), chicken MBP (396217), domestic cat MBP (101096421), dog MBP (476160), sheep MBP (101109407), cow MBP (618684), naked mole-rat Mbp (101702488), domestic guinea pig Mbp (100731253)
ID UniProtKB:
ID gene:
- Human(4155) Summary: The protein encoded by the classic MBP gene is a major constituent of the myelin sheath of oligodendrocytes and Schwann cells in the nervous system. However, MBP-related transcripts are also present in the bone marrow and the immune system. These mRNAs arise from the long MBP gene (otherwise called 'Golli-MBP') that contains 3 additional exons located upstream of the classic MBP exons. Alternative splicing from the Golli and the MBP transcription start sites gives rise to 2 sets of MBP-related transcripts and gene products. The Golli mRNAs contain 3 exons unique to Golli-MBP, spliced in-frame to 1 or more MBP exons. They encode hybrid proteins that have N-terminal Golli aa sequence linked to MBP aa sequence. The second family of transcripts contain only MBP exons and produce the well characterized myelin basic proteins. This complex gene structure is conserved among species suggesting that the MBP transcription unit is an integral part of the Golli transcription unit and that this arrangement is important for the function and/or regulation of these genes. [provided by RefSeq, Jul 2008]
- Mouse(17196) myelin basic protein
- Rat(24547) myelin basic protein
- chicken(396217) myelin basic protein
- domestic cat(101096421) myelin basic protein
- dog(476160) myelin basic protein
- sheep(101109407) myelin basic protein
- cow(618684) myelin basic protein
- naked mole-rat(101702488) myelin basic protein
- domestic guinea pig(100731253) myelin basic protein
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Antibodies
N° Catalogo
Descrizione
Reattività con
Applicazione
Monoclonal Anti-MBP antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL2829, purified immunoglobulin, buffered aqueous glycerol solution,
Reattività con
human, mouse, rat
Applicazione
immunohistochemistry
western blot
western blot
Anti-Myelin Basic Protein Mouse mAb (SMI-99), liquid, clone SMI-99, Calbiochem®,
Reattività con
guinea pig, mammals
Applicazione
Monoclonal Anti-MBP antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL2827, purified immunoglobulin, buffered aqueous glycerol solution,
Reattività con
human, mouse, rat
Applicazione
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-MBP, affinity isolated antibody,
Reattività con
dog, guinea pig, horse, human, rabbit, rat
Applicazione
western blot
Monoclonal Anti-Myelin Basic Protein (MBP) (36-50) antibody produced in rat, clone 14, tissue culture supernatant,
Reattività con
chicken, horse, human
Applicazione
ELISA
immunofluorescence
immunohistochemistry
immunofluorescence
immunohistochemistry
Proteins
N° Catalogo
Descrizione
Specie
Proteina basica della mielina, ≥90% (SDS-PAGE), lyophilized powder, suitable for activity assay,
Specie
cow
Myelin Basic Protein from guinea pig brain, ≥80% (SDS-PAGE), lyophilized powder, from guinea pig brain,
Specie
domestic guinea pig
esiRNA
N° Catalogo
Descrizione
Specie