LRRK2
leucine-rich repeat kinase 2
Sinonimi:
AURA17, DARDARIN, PARK8, RIPK7, ROCO2
Specie:
Human LRRK2 (120892), Mouse Lrrk2 (66725), Rat Lrrk2 (300160), Zebrafish lrrk2 (559366), dog LRRK2 (486608), cow LRRK2 (535652), domestic cat LRRK2 (101096157), sheep LRRK2 (101111447), naked mole-rat Lrrk2 (101708809), chicken LRRK2 (427844)
ID UniProtKB:
ID gene:
- Human(120892) Summary: This gene is a member of the leucine-rich repeat kinase family and encodes a protein with an ankryin repeat region, a leucine-rich repeat (LRR) domain, a kinase domain, a DFG-like motif, a RAS domain, a GTPase domain, a MLK-like domain, and a WD40 domain. The protein is present largely in the cytoplasm but also associates with the mitochondrial outer membrane. Mutations in this gene have been associated with Parkinson disease-8. [provided by RefSeq, Jul 2008]
- Mouse(66725) leucine-rich repeat kinase 2
- Rat(300160) leucine-rich repeat kinase 2
- Zebrafish(559366) leucine-rich repeat kinase 2
- dog(486608) leucine-rich repeat kinase 2
- cow(535652) leucine-rich repeat kinase 2
- domestic cat(101096157) leucine-rich repeat kinase 2
- sheep(101111447) leucine-rich repeat kinase 2
- naked mole-rat(101708809) leucine-rich repeat kinase 2
- chicken(427844) leucine-rich repeat kinase 2
- domestic guinea pig(100730338) leucine-rich repeat kinase 2
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Antibodies
N° Catalogo
Descrizione
Reattività con
Applicazione
Anti-LRRK2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-LRRK2 Antibody, clone N138/6, clone N138/6, from mouse,
Reattività con
human, mouse
Applicazione
immunohistochemistry
western blot
western blot
Anti-LRRK2/PARK8 Antibody, clone 1C17 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reattività con
bovine, canine, horse, human, monkey, mouse, porcine
Applicazione
affinity binding assay
immunocytochemistry
immunohistochemistry
western blot
immunocytochemistry
immunohistochemistry
western blot
Anti-LRRK2 Antibody, from rabbit, purified by affinity chromatography,
Reattività con
human, mouse
Applicazione
immunofluorescence
immunohistochemistry
immunoprecipitation (IP)
western blot
immunohistochemistry
immunoprecipitation (IP)
western blot
Anti-Phospho-LRRK2-S935 antibody produced in rabbit, ,
Reattività con
human, mouse, rat
Applicazione
western blot
Proteins
N° Catalogo
Descrizione
Specie
LRRK2 Protein, active, 10 µg, Active, N-terminal FLAG-tagged, recombinant, human LRRK2, amino acids 970-end. For use in Kinase Assays.,
Specie
human