LCK
lymphocyte-specific protein tyrosine kinase
Sinonimi:
LSK, YT16, p56lck, pp58lck
Specie:
Human LCK (3932), Mouse Lck (16818), Rat Lck (313050), chicken LCK (396460), Zebrafish lck (414333), domestic cat LCK (101098805), dog LCK (478151), Domestic Rabbit LCK (100349102), sheep LCK (100216439), cow LCK (508890) ...Più
ID UniProtKB:
ID gene:
- Human(3932) Summary: This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein is a key signaling molecule in the selection and maturation of developing T-cells. It contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to the plasma membrane and pericentrosomal vesicles, and binds to cell surface receptors, including CD4 and CD8, and other signaling molecules. Multiple alternatively spliced variants, encoding the same protein, have been described. [provided by RefSeq, Jul 2008]
- Mouse(16818) lymphocyte protein tyrosine kinase
- Rat(313050) lymphocyte-specific protein tyrosine kinase
- chicken(396460) lymphocyte-specific protein tyrosine kinase
- Zebrafish(414333) lymphocyte-specific protein tyrosine kinase
- domestic cat(101098805) lymphocyte-specific protein tyrosine kinase
- dog(478151) lymphocyte-specific protein tyrosine kinase
- Domestic Rabbit(100349102) lymphocyte-specific protein tyrosine kinase
- sheep(100216439) lymphocyte-specific protein tyrosine kinase
- cow(508890) lymphocyte-specific protein tyrosine kinase
- Horse(100146139) lymphocyte-specific protein tyrosine kinase
- naked mole-rat(101714396) lymphocyte-specific protein tyrosine kinase
- domestic guinea pig(100728811) lymphocyte-specific protein tyrosine kinase
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ELISA
N° Catalogo
Descrizione
Specie
Small Molecule - Antagonist
Antibodies
N° Catalogo
Descrizione
Reattività con
Applicazione
Anti-phospho-LCK (pTyr394) antibody produced in rabbit, affinity isolated antibody,
Reattività con
human, mouse, rat
Applicazione
western blot
Anti-LCK antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-phospho-Lck (pTyr393) antibody produced in rabbit, affinity isolated antibody,
Reattività con
human, mouse, rat
Applicazione
ELISA
immunofluorescence
western blot
immunofluorescence
western blot
Anti-Phospho-LCK-Y394 antibody produced in rabbit, ,
Reattività con
human, mouse, rat
Applicazione
western blot
Anti-Lck Antibody, clone 2B20 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reattività con
human
Applicazione
affinity binding assay
flow cytometry
immunocytochemistry
immunohistochemistry
western blot
flow cytometry
immunocytochemistry
immunohistochemistry
western blot
Small Molecule - Inhibitor
N° Catalogo
Descrizione
Specie
7-Cyclopentyl-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3‑d]pyrimidin-4-ylamine, ≥98% (HPLC),
Specie
human
Proteins
N° Catalogo
Descrizione
Specie
LCK, active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Specie
human