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Merck

IKBKG

inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma

Sinonimi:
AMCBX1, FIP-3, FIP3, Fip3p, IKK-gamma, IP, IP1, IP2, IPD2, NEMO, ZC2HC9
Specie:
ID UniProtKB:
ID gene:
  • Human(8517) Summary: This gene encodes the regulatory subunit of the inhibitor of kappaB kinase (IKK) complex, which activates NF-kappaB resulting in activation of genes involved in inflammation, immunity, cell survival, and other pathways. Mutations in this gene result in incontinentia pigmenti, hypohidrotic ectodermal dysplasia, and several other types of immunodeficiencies. Multiple transcript variants encoding different isoforms have been found for this gene. A pseudogene highly similar to this locus is located in an adjacent region of the X chromosome. [provided by RefSeq, Aug 2011]
  • Mouse(16151) inhibitor of kappaB kinase gamma
  • Rat(309295) inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
  • Domestic Rabbit(100328905) inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
  • domestic guinea pig(100722308) inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
  • naked mole-rat(101712077) inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
  • dog(612576) inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
  • domestic cat(101086544) inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
  • cow(281855) inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
  • Zebrafish(541530) inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
  • sheep(101107332) inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma

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Small Molecule - Antagonist

N° Catalogo
Descrizione
Specie
Parthenolide, ≥98% (HPLC),
Specie
human

Antibodies

N° Catalogo
Descrizione
Reattività con
Applicazione
Anti-IKBKG antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human, mouse, rat
Applicazione
immunofluorescence
immunohistochemistry

western blot
Anti-IKK-γ antibody produced in rabbit, affinity isolated antibody,
Reattività con
human
Applicazione
ELISA
immunohistochemistry

western blot
Anti-IKKγ antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Reattività con
human, mouse, rat
Applicazione
ELISA
immunocytochemistry

western blot
Anti-IKKγ Antibody, Upstate®, from mouse,
Reattività con
human, mouse
Applicazione
western blot
Anti-Phospho-IKKγ-S376 antibody produced in rabbit, ,
Reattività con
human, mouse
Applicazione
immunohistochemistry
western blot

Proteins

N° Catalogo
Descrizione
Specie
IKK-γ, GST tagged human, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Specie
human

esiRNA

N° Catalogo
Descrizione
Specie
MISSION® esiRNA, targeting human IKBKG,
Specie
human