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Merck

HRH3

histamine receptor H3

Sinonimi:
GPCR97, HH3R
Specie:
Human HRH3 (11255), Mouse Hrh3 (99296), Rat Hrh3 (85268), sheep HRH3 (101121700), Domestic Rabbit HRH3 (100009035), chicken HRH3 (428147), dog HRH3 (477282), domestic cat HRH3 (101084437), cow HRH3 (789851), Zebrafish hrh3 (561773)
ID UniProtKB:
Q9Y5N1, Q4QRI7, Q9GZX2, Q9H4K8
ID gene:
  • Human(11255) Summary: Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. This gene encodes one of the histamine receptors (H3) which belongs to the family 1 of G protein-coupled receptors. It is an integral membrane protein and can regulate neurotransmitter release. This receptor can also increase voltage-dependent calcium current in smooth muscles and innervates the blood vessels and the heart in cardiovascular system. [provided by RefSeq, Jul 2008]
  • Mouse(99296) histamine receptor H3
  • Rat(85268) histamine receptor H3
  • sheep(101121700) histamine receptor H3
  • Domestic Rabbit(100009035) histamine receptor H3
  • chicken(428147) histamine receptor H3
  • dog(477282) histamine receptor H3
  • domestic cat(101084437) histamine receptor H3
  • cow(789851) histamine receptor H3
  • Zebrafish(561773) histamine receptor H3
  • domestic guinea pig(100135541) histamine receptor H3

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Small Molecule - Agonist

Numero di prodotto
Descrizione
Specie
H128
(R)(−)-α-Methylhistamine dihydrochloride, solid, ≥98% (HPLC),
Specie
human
I135
Imetit dihydrobromide, ≥98% (HPLC),
Specie
human
B4638
Betahistine dihydrochloride, ≥98%,
Specie
human
PHR2097
Betahistine Hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material,
Specie
human
1065618
Betahistine hydrochloride, United States Pharmacopeia (USP) Reference Standard,
Specie
human

Small Molecule - Antagonist

Numero di prodotto
Descrizione
Specie
T123
Thioperamide maleate salt, solid,
Specie
human
B4638
Betahistine dihydrochloride, ≥98%,
Specie
human
PHR2097
Betahistine Hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material,
Specie
human
1065618
Betahistine hydrochloride, United States Pharmacopeia (USP) Reference Standard,
Specie
human
M28804
2-(2-Methylaminoethyl)pyridine, 97%,
Specie
human

Antibodies

Numero di prodotto
Descrizione
Reattività con
Applicazione
SAB5701457
Anti-HRH3 antibody produced in rabbit, ,
Reattività con
human, mouse, rat
Applicazione
immunohistochemistry
western blot

Small Molecule - Inhibitor

Numero di prodotto
Descrizione
Specie
H7125
Histamine, ≥97.0%,
Specie
human, rat

Small Molecule - Metabolite

Numero di prodotto
Descrizione
Specie
M4910
1-Methylhistamine dihydrochloride, ≥98% (TLC), powder,
Specie
human

esiRNA

Numero di prodotto
Descrizione
Specie
EHU141391
MISSION® esiRNA, targeting human HRH3,
Specie
human