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Merck

HRH1

histamine receptor H1

Sinonimi:
H1-R, hisH1
Specie:
ID UniProtKB:
ID gene:
  • Human(3269) Summary: Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. This gene was thought to be intronless until recently. The protein encoded by this gene is an integral membrane protein and belongs to the G protein-coupled receptor superfamily. It mediates the contraction of smooth muscles, the increase in capillary permeability due to contraction of terminal venules, the release of catecholamine from adrenal medulla, and neurotransmission in the central nervous system. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]
  • Mouse(15465) histamine receptor H1
  • Rat(24448) histamine receptor H 1
  • naked mole-rat(101715481) histamine receptor H1
  • domestic cat(101088314) histamine receptor H1
  • domestic guinea pig(100135539) histamine receptor H1
  • chicken(100858928) histamine receptor H1
  • domestic guinea pig(100730517) histamine receptor H1
  • cow(281231) histamine receptor H1
  • dog(403813) histamine receptor H1
  • Zebrafish(735302) histamine receptor H1
  • Horse(100034110) histamine receptor H1
  • sheep(101121717) histamine receptor H1

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Small Molecule - Agonist

N° Catalogo
Descrizione
Specie
Histamine dihydrochloride, ≥99.0% (AT),
Specie
human
Histamine, analytical standard,
Specie
human
Histamine dihydrochloride, United States Pharmacopeia (USP) Reference Standard,
Specie
human
Histamine, European Pharmacopoeia (EP) Reference Standard,
Specie
human
Histamine dihydrochloride, European Pharmacopoeia (EP) Reference Standard,
Specie
human

Small Molecule - Antagonist

N° Catalogo
Descrizione
Specie
Pheniramine maleate, United States Pharmacopeia (USP) Reference Standard,
Specie
human
Diphenhydramine hydrochloride, ≥98% (HPLC),
Specie
human
Chlorpheniramine Maleate, Pharmaceutical Secondary Standard; Certified Reference Material,
Specie
human
Diphenhydramine hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material,
Specie
human
Cetirizine, ≥98% (HPLC),
Specie
human

Antibodies

N° Catalogo
Descrizione
Reattività con
Applicazione
Monoclonal Anti-HRH1 antibody produced in mouse, clone 3D1, purified immunoglobulin, buffered aqueous solution,
Reattività con
human
Applicazione
ELISA
proximity ligation assay
Anti-Histamine Receptor 1 Antibody, CT, Chemicon®, from rabbit,
Reattività con
bovine, mouse, rat
Applicazione
ELISA
western blot

Small Molecule - Blocker

N° Catalogo
Descrizione
Specie
Cinnarizine, European Pharmacopoeia (EP) Reference Standard,
Specie
human
Mianserin hydrochloride, ,
Specie
human
Cinnarizine, powder,
Specie
human
Orphenadrine hydrochloride, ≥98.0% (AT),
Specie
human
Orphenadrine for peak identification, European Pharmacopoeia (EP) Reference Standard,
Specie
human

Small Molecule - Inhibitor

N° Catalogo
Descrizione
Specie
Ketotifen fumarate salt, ,
Specie
human
L-Histidinol dihydrochloride, ≥98 (TLC),
Specie
mouse, rat, human
D-Histidine monohydrochloride monohydrate, ≥98% (TLC),
Specie
mouse, rat, human
Loratadine, ≥98% (HPLC), powder,
Specie
rat, human
Histamine, ≥97.0%,
Specie
human, rat

Small Molecule - Ligand

N° Catalogo
Descrizione
Specie
Loratadine, ≥98% (HPLC), powder,
Specie
rat, human
Cinnarizine, powder,
Specie
human

Small Molecule - Metabolite

N° Catalogo
Descrizione
Specie
1-Methylhistamine dihydrochloride, ≥98% (TLC), powder,
Specie
human

Small Molecule - Mixed Agonist/Antagonist

N° Catalogo
Descrizione
Specie
2-(2-Pyridyl)ethylamine, 95%,
Specie
human
Haloperidol, powder,
Specie
human, rat
Clozapine, ,
Specie
human, rat

esiRNA

N° Catalogo
Descrizione
Specie
MISSION® esiRNA, targeting mouse Hrh1,
Specie
mouse
MISSION® esiRNA, targeting human HRH1,
Specie
human