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Merck

GLUD1

glutamate dehydrogenase 1

Sinonimi:
GDH, GDH1, GLUD
Specie:
ID UniProtKB:
ID gene:
  • Human(2746) Summary: This gene encodes glutamate dehydrogenase protein; a mitochondrial matrix enzyme that catalyzes the oxidative deamination of glutamate to alpha-ketoglutarate and ammonia. This enzyme has an important role in regulating amino acid induced insulin secretion and activating mutations in this gene are a common cause of congenital hyperinsulinism. This enzyme is allosterically activated by ADP and inhibited by GTP and ATP. The related glutamate dehydrogenase 2 gene on the human X-chromosome originated from this gene via retrotransposition and encodes a soluble form of glutamate dehydrogenase. Multiple pseudogenes of this gene are present in humans.[provided by RefSeq, Sep 2009]
  • Mouse(14661) glutamate dehydrogenase 1
  • Rat(24399) glutamate dehydrogenase 1
  • naked mole-rat(101699446) glutamate dehydrogenase 1
  • domestic guinea pig(100722523) glutamate dehydrogenase 1
  • sheep(443239) glutamate dehydrogenase 1
  • cow(281785) glutamate dehydrogenase 1
  • dog(100684847) glutamate dehydrogenase 1
  • chicken(423612) glutamate dehydrogenase 1

Custom & Knockdown Gene Products

Antibodies

Numero di prodotto
Descrizione
Reattività con
Applicazione
Anti-GLUD1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reattività con
human
Applicazione
immunofluorescence
western blot
Anti-GLUD1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunohistochemistry
Anti-GLUD1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunofluorescence
immunohistochemistry

western blot
Anti-GLUD1 antibody produced in rabbit, ,
Reattività con
human, mouse, rat
Applicazione
immunohistochemistry
western blot
Anti-GLUD1, affinity isolated antibody,
Reattività con
bovine, dog, horse, human, mouse, pig, rabbit, rat, sheep
Applicazione
immunohistochemistry
western blot

Proteins

Numero di prodotto
Descrizione
Specie
Glutamate Dehydrogenase (GlDH), from beef liver,
Specie
cow
L-Glutamic Dehydrogenase from bovine liver, Type III, lyophilized powder, ≥20 units/mg protein,
Specie
cow
L-Glutamic Dehydrogenase from bovine liver, Type I, ammonium sulfate suspension, ≥40 units/mg protein,
Specie
cow

esiRNA

Numero di prodotto
Descrizione
Specie
MISSION® esiRNA, targeting human GLUD1,
Specie
human
MISSION® esiRNA, targeting mouse Glud1,
Specie
mouse