Passa al contenuto
Merck

CYP1A2

cytochrome P450, family 1, subfamily A, polypeptide 2

Sinonimi:
CP12, P3-450, P450(PA)
Specie:
Human CYP1A2 (1544), Mouse Cyp1a2 (13077), Rat Cyp1a2 (24297), domestic guinea pig Cyp1a2 (100135513), domestic cat CYP1A2 (554345), chicken CYP1A2 (414856), cow CYP1A2 (503552), dog CYP1A2 (494010)
ID UniProtKB:
P05177, Q16754, Q6NWU5, Q9BXX7, Q9UK49
ID gene:
  • Human(1544) Summary: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The protein encoded by this gene localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. Other xenobiotic substrates for this enzyme include caffeine, aflatoxin B1, and acetaminophen. The transcript from this gene contains four Alu sequences flanked by direct repeats in the 3' untranslated region. [provided by RefSeq, Jul 2008]
  • Mouse(13077) cytochrome P450, family 1, subfamily a, polypeptide 2
  • Rat(24297) cytochrome P450, family 1, subfamily a, polypeptide 2
  • domestic guinea pig(100135513) cytochrome P450, family 1, subfamily a, polypeptide 2
  • domestic cat(554345) cytochrome P450 1A2
  • chicken(414856) cytochrome P450, family 1, subfamily A, polypeptide 2
  • cow(503552) cytochrome P450, family 1, subfamily A, polypeptide 2
  • dog(494010) cytochrome P450, family 1, subfamily A, polypeptide 2

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Numero di prodotto
Descrizione
Reattività con
Applicazione
AB1248
Anti-Cytochrome P450 Enzyme CYP1A2 Antibody, serum, Chemicon®,
Reattività con
human
Applicazione
immunohistochemistry
western blot
SAB1401102
Anti-CYP1A2 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Reattività con
human
Applicazione
western blot

Small Molecule - Inhibitor

Numero di prodotto
Descrizione
Specie
C0378
Cloramfenicolo, ≥98% (HPLC),
Specie
human
183164
(R)-(+)-Limonene, 97%,
Specie
human
A88107
p-Anisaldehyde, 98%,
Specie
human
N1000
1-Naphthol, ReagentPlus®, ≥99%,
Specie
human
147141
Naphthalene, 99%,
Specie
human

Proteins

Numero di prodotto
Descrizione
Specie
MTOXCE1A2
CypExpress™ 1A2 Cytochrome P450 human, ,
Specie
human
C5614
Cytochrome P450 human, 1A2 Isozyme Microsomes, with P450 Reductase and cytochrome b5, recombinant, expressed in baculovirus infected insect cells (BTI-TN-5B1-4),
Specie
human

esiRNA

Numero di prodotto
Descrizione
Specie
EHU001461
MISSION® esiRNA, targeting human CYP1A2,
Specie
human