Passa al contenuto
Merck

CSF1R

colony stimulating factor 1 receptor

Sinonimi:
C-FMS, CD115, CSF-1R, CSFR, FIM2, FMS, HDLS, M-CSF-R
Specie:
ID UniProtKB:
ID gene:
  • Human(1436) Summary: The protein encoded by this gene is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases. Mutations in this gene have been associated with a predisposition to myeloid malignancy. The first intron of this gene contains a transcriptionally inactive ribosomal protein L7 processed pseudogene oriented in the opposite direction. [provided by RefSeq, Jul 2008]
  • Mouse(12978) colony stimulating factor 1 receptor
  • Rat(307403) colony stimulating factor 1 receptor
  • domestic guinea pig(100726053) colony stimulating factor 1 receptor
  • naked mole-rat(101719513) colony stimulating factor 1 receptor
  • sheep(101109969) colony stimulating factor 1 receptor
  • cow(509418) colony stimulating factor 1 receptor
  • domestic cat(493706) colony stimulating factor 1 receptor
  • Horse(100060422) colony stimulating factor 1 receptor
  • dog(489188) colony stimulating factor 1 receptor
  • chicken(396406) colony stimulating factor 1 receptor

Custom & Knockdown Gene Products

ELISA

Numero di prodotto
Descrizione
Specie
Human CSF1R / Macrophage Colony-stimulating Factor 1 Receptor ELISA Kit, ,
Specie
human
Phosphotyrosine CSF1R / Macrophage Colony-stimulating Factor 1 Receptor ELISA Kit, ,
Specie
human

Antibodies

Numero di prodotto
Descrizione
Reattività con
Applicazione
Anti-CSF-1R antibody, Rabbit monoclonal, recombinant, expressed in proprietary host, clone SP211, affinity isolated antibody,
Reattività con
human, mouse, rat
Applicazione
immunohistochemistry
Anti-CSF1R antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunofluorescence
immunohistochemistry

western blot
Anticorpo anti-CSF-1R/CD115, clone FER216, clone FER216, from mouse,
Reattività con
human
Applicazione
western blot
Monoclonal Anti-CSF1R antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL11653, purified immunoglobulin, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunofluorescence
Anti-CSF1R/c-FMS Antibody, clone AFS98, ,
Reattività con
mouse
Applicazione
flow cytometry

Small Molecule - Inhibitor

Numero di prodotto
Descrizione
Specie
Pazopanib, ,
Specie
human

Proteins

Numero di prodotto
Descrizione
Specie
FMS (539-end), active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Specie
human

esiRNA

Numero di prodotto
Descrizione
Specie
MISSION® esiRNA, targeting mouse Csf1r,
Specie
mouse
MISSION® esiRNA, targeting human CSF1R,
Specie
human