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Merck

ADRA2C

adrenoceptor alpha 2C

Sinonimi:
ADRA2L2, ADRA2RL2, ADRARL2, ALPHA2CAR
Specie:
ID UniProtKB:
ID gene:
  • Human(152) Summary: Alpha-2-adrenergic receptors are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. The mouse studies revealed that both the alpha2A and alpha2C subtypes were required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and from central noradrenergic neurons. The alpha2A subtype inhibited transmitter release at high stimulation frequencies, whereas the alpha2C subtype modulated neurotransmission at lower levels of nerve activity. This gene encodes the alpha2C subtype, which contains no introns in either its coding or untranslated sequences. [provided by RefSeq, Jul 2008]
  • Mouse(11553) adrenergic receptor, alpha 2c
  • Rat(24175) adrenoceptor alpha 2C
  • domestic guinea pig(100135477) adrenergic receptor, alpha 2c
  • domestic guinea pig(101787589) adrenoceptor alpha 2C
  • cow(101902575) adrenoceptor alpha 2C
  • cow(407139) alpha-2C adrenergic receptor
  • sheep(100170319) adrenoceptor alpha 2C
  • Zebrafish(266752) adrenergic, alpha-2C-, receptor
  • chicken(428799) adrenergic, alpha-2C-, receptor
  • dog(488793) adrenoceptor alpha 2C
  • domestic cat(101087990) adrenoceptor alpha 2C
  • domestic cat(100529244) adrenoceptor alpha 2C

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Small Molecule - Agonist

N° Catalogo
Descrizione
Specie
Clonidine hydrochloride, solid,
Specie
human
Xylazine hydrochloride, ≥99.0% (HPLC),
Specie
human
Guanfacine hydrochloride, United States Pharmacopeia (USP) Reference Standard,
Specie
human
Guanfacine hydrochloride, ≥98% (HPLC),
Specie
human
Guanabenz acetate salt, powder,
Specie
human

Small Molecule - Antagonist

N° Catalogo
Descrizione
Specie
Yohimbine hydrochloride, ≥98% (HPLC), powder,
Specie
human
Idazoxan hydrochloride, ,
Specie
human
RX 821002 hydrochloride, solid, ≥98% (HPLC),
Specie
human
UK 14,304, ,
Specie
human
Mirtazapine solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Specie
human

Antibodies

N° Catalogo
Descrizione
Reattività con
Applicazione
Monoclonal Anti-Alpha 2C Adrenergic Receptor - Apc antibody produced in mouse, clone S330A-80, purified immunoglobulin,
Reattività con
human, mouse
Applicazione
immunocytochemistry
western blot
Anti-Adrenergic Receptor α-2C antibody produced in rabbit, affinity isolated antibody,
Reattività con
human, mouse, rat
Applicazione
ELISA
western blot
Monoclonal Anti-Alpha 2C Adrenergic Receptor - Atto 488 antibody produced in mouse, clone S330A-80, purified immunoglobulin,
Reattività con
human, mouse
Applicazione
immunocytochemistry
western blot
Monoclonal Anti-Alpha 2C Adrenergic Receptor - Rpe antibody produced in mouse, clone S330A-80, purified immunoglobulin,
Reattività con
human, mouse
Applicazione
immunocytochemistry
western blot
Monoclonal Anti-Alpha 2C Adrenergic Receptor - Atto 390 antibody produced in mouse, clone S330A-80, purified immunoglobulin,
Reattività con
human, mouse
Applicazione
immunocytochemistry
western blot

Small Molecule - Blocker

N° Catalogo
Descrizione
Specie
Mianserin hydrochloride, ,
Specie
human
Agmatine sulfate salt, ≥97%, powder,
Specie
human

Small Molecule - Mixed Agonist/Antagonist

N° Catalogo
Descrizione
Specie
UK 14,304, ,
Specie
human
(−)-Norepinephrine, ≥98%, crystalline,
Specie
human, rat
Haloperidol, powder,
Specie
human, rat
Clozapine, ,
Specie
human, rat

esiRNA

N° Catalogo
Descrizione
Specie
MISSION® esiRNA, targeting mouse Adra2c,
Specie
mouse